在一项纵向队列研究中，在首次阴道性交前阴道内人乳头瘤病毒检测的高频率。
High frequency of human papillomavirus detection in the vagina before first vaginal intercourse among females enrolled in a longitudinal cohort study.
机构信息
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
出版信息
J Infect Dis. 2013 Mar 15;207(6):1012-5. doi: 10.1093/infdis/jis775. Epub 2012 Dec 13.
Abstract
BACKGROUND
Genital human papillomavirus (HPV) infection is believed to be primarily sexually transmitted. Few studies have documented the detection of HPV in the vagina before first vaginal intercourse.
METHODS
We used a longitudinally followed cohort of adolescent females without prior vaginal intercourse to examine the frequency of detection of vaginal HPV and the association between first reported HPV detection and noncoital sexual behaviors.
RESULTS
HPV was detected in 45.5% of subjects (10 of 22) before first vaginal sex. Seven of these 10 subjects reported noncoital behaviors that, in part, might have explained genital transmission.
CONCLUSIONS
HPV can be detected in the vagina before first sexual intercourse, highlighting the need for early vaccination.
摘要
背景
生殖器人乳头瘤病毒（HPV）感染被认为主要通过性传播。很少有研究记录到在首次阴道性交前阴道内 HPV 的检测。
方法
我们使用一组纵向随访的无既往阴道性交的青春期女性队列，研究阴道 HPV 的检测频率，以及首次报告的 HPV 检测与非性交性行为之间的关系。
结果
在首次阴道性交前，45.5%的受试者（22 名中的 10 名）检测出 HPV。这 10 名受试者中的 7 名报告了非性交行为，这些行为可能部分解释了生殖器传播。
结论
HPV 可在首次性交前阴道内检测到，这突出了早期接种疫苗的必要性。
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