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儿童肿瘤学组 2013 年研究蓝图:行为科学。

Children's Oncology Group's 2013 blueprint for research: behavioral science.

机构信息

Department of Pediatrics, University of Pittsburgh Medical Center, Pittsburgh, PA 15217, USA.

出版信息

Pediatr Blood Cancer. 2013 Jun;60(6):1048-54. doi: 10.1002/pbc.24421. Epub 2012 Dec 19.

DOI:10.1002/pbc.24421
PMID:23255478
Abstract

Behavioral science has long played a central role in pediatric oncology clinical service and research. Early work focused on symptom relief related to side effects of chemotherapy and pain management related to invasive medical procedures. As survival rates improved, the focused has shifted to examination of the psychosocial impact, during and after treatment, of pediatric cancer and its treatment on children and their families. The success of the clinical trials networks related to survivorship highlights an even more critical role in numerous domains of psychosocial research and care. Within the cooperative group setting, the field of behavioral science includes psychologists, social workers, physicians, nurses, and parent advisors. The research agenda of this group of experts needs to focus on utilization of psychometrically robust measures to evaluate the impact of treatment on children with cancer and their families during and after treatment ends. Over the next 5 years, the field of behavioral science will need to develop and implement initiatives to expand use of standardized neurocognitive and behavior batteries; increase assessment of neurocognition using technology; early identification of at-risk children/families; establish standards for evidence-based psychosocial care; and leverage linkages with the broader behavioral health pediatric oncology community to translate empirically supported research clinical trials care to practice.

摘要

行为科学在儿科肿瘤临床服务和研究中一直发挥着核心作用。早期的工作重点是缓解化疗副作用相关的症状和与侵入性医疗程序相关的疼痛管理。随着生存率的提高,研究重点已经转移到检查儿童癌症及其治疗对儿童及其家庭在治疗期间和治疗后的心理社会影响。与生存相关的临床试验网络的成功突出了行为科学在众多心理社会研究和护理领域的更关键作用。在合作组环境中,行为科学领域包括心理学家、社会工作者、医生、护士和家长顾问。这组专家的研究议程需要侧重于利用心理测量学上可靠的措施来评估治疗对癌症儿童及其家庭在治疗结束期间和之后的影响。在未来 5 年内,行为科学领域将需要制定和实施举措,以扩大使用标准化神经认知和行为电池;增加使用技术评估神经认知;早期识别高危儿童/家庭;建立基于证据的心理社会护理标准;并利用与更广泛的行为健康儿科肿瘤社区的联系,将经验支持的研究临床试验护理转化为实践。

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