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妥舒沙星、替马沙星和A-56620对腹泻病原体的体外活性

In vitro activities of tosufloxacin, temafloxacin, and A-56620 against pathogens of diarrhea.

作者信息

Bryan J P, Waters C, Sheffield J, Krieg R E, Perine P L, Wagner K

机构信息

Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

出版信息

Antimicrob Agents Chemother. 1990 Feb;34(2):368-70. doi: 10.1128/AAC.34.2.368.

Abstract

Tosufloxacin (A-60969 HCl), a new quinolone with broad activity against gram-positive and anaerobic organisms, was compared in vitro with other quinolones against bacterial pathogens of diarrhea. Tosufloxacin was the most active agent against Salmonella spp., Shigella spp., Campylobacter spp., Aeromonas hydrophila, and Vibrio spp. Temafloxacin (A-62254) also demonstrated good activity against these organisms.

摘要

托氟沙星(盐酸A-60969)是一种对革兰氏阳性菌和厌氧菌具有广泛活性的新型喹诺酮类药物,在体外将其与其他喹诺酮类药物针对腹泻病原菌进行了比较。托氟沙星对沙门氏菌属、志贺氏菌属、弯曲菌属、嗜水气单胞菌和弧菌属是活性最强的药物。替马沙星(A-62254)对这些菌也显示出良好活性。

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