St George's, University of London, London, UK.
Respir Med. 2012 Dec;106 Suppl 2:S86-99. doi: 10.1016/S0954-6111(12)70017-3.
The objective of this study was to assess the validity and performance of the Arabic and Turkish versions of the COPD Assessment Test (CAT) for evaluating the severity and impact of COPD symptoms. The data were obtained from the BREATHE study in the Middle East and North Africa region, a large general population survey of COPD conducted in ten countries of the region (Algeria, Egypt, Jordan, Lebanon, Morocco, Saudi Arabia, Syria, Tunisia, Turkey and United Arab Emirates), using a standardised methodology. A total of 62,086 subjects were screened, of whom a random sample of 5,681 subjects were administered the CAT by telephone. 5,639 evaluable questionnaires were recovered, representing a completion rate of 99%. In addition, the CAT was administered to an additional 833 subjects fulfilling the epidemiological diagnostic criteria for COPD. Mean scores in the general population were 6.99 ± 6.91 for the Arabic version and 9.88 ± 9.04 for the Turkish version. In patients with COPD, mean scores were 16.2 ± 9.1 and 20.9 ± 10.2 respectively. Scores were consistently higher in smokers than in non-smokers. In the general population, the proportion of respondents fulfilling criteria for COPD rose with higher CAT scores, and particularly above the 80th percentile, where 63% of COPD cases were to be found. This suggests that the CAT may be useful as a case-finding tool in the general population. In the COPD population, healthcare resource consumption rose linearly with CAT score above a threshold score of twenty, arguing in favour of the good criterion validity of the CAT. The internal consistency of the CAT was high (Cronbach's α 0.85 for the Arabic and 0.86 for the Turkish versions) and the factorial structure was unidimensional. In conclusion, this study performed in Arabic and Turkish speaking populations confirms the utility and validity of the CAT as a simple tool to collect data on the severity and impact of COPD symptoms, and suggests that it may potentially be useful as a case-finding tool to identify people at risk for COPD in the general population.
本研究旨在评估 COPD 评估测试（CAT）的阿拉伯语和土耳其语版本评估 COPD 症状严重程度和影响的有效性和性能。数据来自中东和北非地区的 BREATHE 研究，这是该地区十个国家进行的一项大型 COPD 普通人群调查，采用标准化方法。共筛选了 62086 名受试者，其中 5681 名随机样本通过电话接受了 CAT 测试。共收回了 5639 份可评估的问卷，完成率为 99%。此外，CAT 还被用于另外 833 名符合 COPD 流行病学诊断标准的患者。一般人群的平均得分分别为阿拉伯语版的 6.99±6.91 和土耳其语版的 9.88±9.04。在 COPD 患者中，平均得分分别为 16.2±9.1 和 20.9±10.2。吸烟者的得分始终高于不吸烟者。在一般人群中，符合 COPD 标准的受访者比例随着 CAT 得分的升高而升高，尤其是在 80%的百分位以上，其中 63%的 COPD 病例都可以找到。这表明 CAT 可能是一种有用的一般人群病例发现工具。在 COPD 人群中，医疗资源消耗随着 CAT 得分高于二十的阈值线性上升，这支持了 CAT 的良好标准有效性。CAT 的内部一致性较高（阿拉伯语版为 0.85，土耳其语版为 0.86），且因素结构是单维的。总之，这项在讲阿拉伯语和土耳其语的人群中进行的研究证实了 CAT 作为一种简单工具收集 COPD 症状严重程度和影响数据的实用性和有效性，并表明它可能作为一种在普通人群中发现 COPD 风险人群的病例发现工具具有潜在的用处。
