电压门控钾通道的C型失活：孔道收缩还是扩张？ - Suppr

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超能文献

C-type inactivation of voltage-gated K+ channels: pore constriction or dilation?

作者信息

Hoshi Toshinori, Armstrong Clay M

机构信息

Department of Physiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

J Gen Physiol. 2013 Feb;141(2):151-60. doi: 10.1085/jgp.201210888. Epub 2013 Jan 14.

DOI:10.1085/jgp.201210888

PMID:23319730

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3557304/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1bc/3557304/adbbdca64fb8/JGP_201210888_Fig1.jpg

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Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6331-6. doi: 10.1073/pnas.1119268109. Epub 2012 Apr 2.

Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.自由能分子动力学模拟揭示钾通道激活和失活门控之间的热力学偶联。

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