Department of Medicine and Diabetology, Saint John's Hospital, Budapest, Hungary.
Med Sci Monit. 2013 Jan 24;19:67-72. doi: 10.12659/msm.883747.
The prevalence of type 2 diabetes mellitus is rapidly increasing, worldwide and also in Hungary. Timely diagnosis and early treatment could be aided by targeted screening. Recognizing this, the Hungarian Diabetes Association initiated a risk-stratified screening with the involvement of primary care physicians.
MATERIAL/METHODS: In the first phase of screening, the FINDRISC questionnaire was completed, followed by an oral glucose tolerance test (OGTT) for those with a score of ≥12. Between September 1, 2010 and March 31, 2011, 70,432 non-diabetic adults, who visited their general practitioners for any reason, were involved in the screening. Of these, 68,476 questionnaires proved to be suitable for processing.
From the questionnaires, 28,077 (41.0%) had a score of ≥12. A valid OGTT was performed in 22,846 cases; of this group 3,217 subjects (14.1%) had elevated fasting glucose levels, 5,663 (24.8%) had impaired glucose tolerance, and 1,750 (7.6%) had manifest, previously undiagnosed, diabetes mellitus. Overall, from the valid OGTT group, 46.5% subjects had some degree of glucose intolerance.
Based on the FINDRISC questionnaire, the risk-stratified screening for diabetes mellitus proved to be simple and cost-effective method for the early detection of carbohydrate metabolism disorders. Using this method, the prevalence rate of previously undiagnosed abnormal glucose tolerance was high in adult patients cared for by general practitioners in Hungary.
2 型糖尿病的患病率在全球范围内迅速上升，在匈牙利也是如此。及时诊断和早期治疗可以通过有针对性的筛查来辅助。认识到这一点，匈牙利糖尿病协会启动了一项风险分层筛查，初级保健医生参与其中。
材料/方法：在筛查的第一阶段，完成了 FINDRISC 问卷，如果得分≥12，则进行口服葡萄糖耐量试验（OGTT）。2010 年 9 月 1 日至 2011 年 3 月 31 日，共有 70432 名非糖尿病成年人因任何原因就诊于他们的全科医生，参与了筛查。在这些人中，有 68476 份问卷适合处理。
从问卷中，有 28077 人（41.0%）得分≥12。在 22846 例中进行了有效的 OGTT；在这一组中，有 3217 名受试者（14.1%）空腹血糖升高，5663 名（24.8%）葡萄糖耐量受损，1750 名（7.6%）患有明显的、以前未诊断的糖尿病。总体而言，在有效的 OGTT 组中，46.5%的受试者存在某种程度的葡萄糖耐量异常。
基于 FINDRISC 问卷，糖尿病的风险分层筛查被证明是一种简单且具有成本效益的方法，可早期发现碳水化合物代谢紊乱。使用这种方法，在匈牙利由全科医生照顾的成年患者中，以前未诊断的异常葡萄糖耐量的患病率较高。
