龈沟液作为牙周诊断指标——I：宿主来源的酶和组织分解产物
Gingival crevicular fluid as a periodontal diagnostic indicator--I: Host derived enzymes and tissue breakdown products.
作者信息
Gupta G
机构信息
Department of Periodontics, Institute of Dental Studies and Technologies, Modinagar.
出版信息
J Med Life. 2012 Dec 15;5(4):390-7. Epub 2012 Dec 25.
Abstract
Researchers involved in the delivery of periodontal therapy are currently investigating the possible use of oral fluids in the diagnosis of oral diseases and drug development. Substantial improvements have been made in the understanding of the mediators implicated on the initiation, pathogenesis, and progression of periodontitis. This review will analyze the mechanisms involved in the breakdown of periodontal supporting tissues during chronic periodontitis and highlights the potential array of biomarkers present in gingival crevicular fluid (GCF), which may relate to existing or predicted tissue regions undergoing metabolic change.
摘要
参与牙周治疗的研究人员目前正在研究口腔液体在口腔疾病诊断和药物开发中的潜在用途。在对与牙周炎的发生、发病机制和进展相关的介质的理解方面已经取得了重大进展。本综述将分析慢性牙周炎期间牙周支持组织破坏所涉及的机制，并重点介绍龈沟液（GCF）中存在的一系列潜在生物标志物，这些生物标志物可能与正在经历代谢变化的现有或预测组织区域有关。
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