总状毛霉中β-葡萄糖苷酶合成的调控
Control of beta-glucosidase synthesis in Mucor racemosus.
作者信息
Borgia P, Sypherd P S
出版信息
J Bacteriol. 1977 May;130(2):812-7. doi: 10.1128/jb.130.2.812-817.1977.
Abstract
The beta-glucosidase of Mucor racemosus was shown to be synthesized when the organism was grown in the presence of such diverse carbon sources as glycerol, lactate, xylose, ribose, alpha-methylglucoside, alpha-phenylglucoside, maltose, and cellobiose. Enzyme synthesis was strongly repressed in the presence of hexoses. In addition, exogenous cyclic adenosine 3',5'-monophosphate (cAMP) resulted in enzyme repression. When cAMP was added exogenously after enzyme activity had accumulated, a reversible enzyme inactivation occurred. Growth on disaccharides (maltose or cellobiose) was severely retarded in the presence of cAMP, whereas that on glucose remained unaffected. The results indicate a probable role for cAMP in control of glucosidase synthesis in Mucor.
摘要
当总状毛霉在甘油、乳酸、木糖、核糖、α-甲基葡糖苷、α-苯基葡糖苷、麦芽糖和纤维二糖等多种不同碳源存在的情况下生长时，会合成β-葡萄糖苷酶。在己糖存在时，酶的合成受到强烈抑制。此外，外源性环腺苷酸（cAMP）会导致酶的抑制。当酶活性积累后外源添加cAMP时，会发生可逆的酶失活。在cAMP存在的情况下，在二糖（麦芽糖或纤维二糖）上的生长严重受阻，而在葡萄糖上的生长不受影响。结果表明cAMP在总状毛霉中对葡萄糖苷酶合成的控制中可能发挥作用。
相似文献
1
Control of beta-glucosidase synthesis in Mucor racemosus.
J Bacteriol. 1977 May;130(2):812-7. doi: 10.1128/jb.130.2.812-817.1977.
2
Effect of growth conditions on catabolite repression and cyclic AMP synthesis in Escherichia coli 3000A1.
J Biochem. 1983 Jan;93(1):281-6. doi: 10.1093/oxfordjournals.jbchem.a134164.
3
Catabolite repression in the hyperthermophilic bacterium Thermotoga neapolitana is independent of cAMP.
Microbiology (Reading). 1996 Jan;142 ( Pt 1):139-144. doi: 10.1099/13500872-142-1-139.
4
Cyclic adenosine 3',5'-monophosphate and morphogenesis in Mucor racemosus.
J Bacteriol. 1974 Feb;117(2):432-8. doi: 10.1128/jb.117.2.432-438.1974.
5
Effect of carbon sources on the rates of cyclic AMP synthesis, excretion, and degradation, and the ability to produce beta-galactosidase in Escherichia coli.
Can J Biochem. 1979 Aug;57(8):1073-9. doi: 10.1139/o79-136.
6
Effect of cyclic adenosine-3',5'-monophosphate on the simultaneous synthesis of beta-galactosidase and tryptophanase in Escherichia coli.
Folia Microbiol (Praha). 1980;25(1):16-23. doi: 10.1007/BF02876393.
7
Effect of glucose and its analogues on the accumulation and release of cyclic adenosine 3',5'-monophosphate in a membrane fraction of Escherichia coli: relation to beta-galactosidase synthesis.
J Bacteriol. 1975 May;122(2):669-75. doi: 10.1128/jb.122.2.669-675.1975.
8
Adenosine 3':5'-cyclic monophosphate as mediator of catabolite repression in Escherichia coli.
Proc Natl Acad Sci U S A. 1975 Jun;72(6):2300-4. doi: 10.1073/pnas.72.6.2300.
9
Effects of 8-substituted analogs of cyclic adenosine 3',5'-monophosphate on in vivo and in vitro syntheses of beta-galactosidase in Escherichia coli.
J Bacteriol. 1979 Jun;138(3):671-7. doi: 10.1128/jb.138.3.671-677.1979.
10
[Regulation of beta-galactosidase synthesis in Escherichia coli by exogenous cyclic 3',5'-adenosine monophosphate].
Mikrobiologiia. 1991 Jan-Feb;60(1):65-70.
引用本文的文献
1
Complement Component C5a and Fungal Pathogen Induce Diverse Responses through Crosstalk between Transient Receptor Potential Channel (TRPs) Subtypes in Human Conjunctival Epithelial Cells.
Cells. 2024 Aug 9;13(16):1329. doi: 10.3390/cells13161329.
2
Tricking Arthrinium malaysianum into Producing Industrially Important Enzymes Under 2-Deoxy D-Glucose Treatment.
Front Microbiol. 2016 May 13;7:596. doi: 10.3389/fmicb.2016.00596. eCollection 2016.
3
Glyoxylate cycle in Mucor racemosus.
J Bacteriol. 1980 Jul;143(1):416-21. doi: 10.1128/jb.143.1.416-421.1980.
4
High-frequency heterokaryon formation by Mucor racemosus.
J Bacteriol. 1980 Feb;141(2):565-9. doi: 10.1128/jb.141.2.565-569.1980.
5
Changes in the rate of chitin-plus-chitosan synthesis accompany morphogenesis of Mucor racemosus.
J Bacteriol. 1981 Jun;146(3):945-51. doi: 10.1128/jb.146.3.945-951.1981.
6
Adenosine 3',5'-phosphate in fungi.
Microbiol Rev. 1981 Sep;45(3):462-80. doi: 10.1128/mr.45.3.462-480.1981.
7
Purification of a soluble and a wall-bound form of beta-glucosidase from Mucor racemosus.
J Bacteriol. 1982 Feb;149(2):515-22. doi: 10.1128/jb.149.2.515-522.1982.
8
Role of cAMP in the mediation of glucose catabolite repression of glucoamylase synthesis in Aspergillus awamori.
Curr Genet. 1988 Sep;14(3):247-52. doi: 10.1007/BF00376745.
9
Optimization of cellulase production by Aspergillus niger NCIM 1207.
Appl Biochem Biotechnol. 1991 Jul;30(1):99-109. doi: 10.1007/BF02922026.
10
Mucor dimorphism.
Microbiol Rev. 1991 Jun;55(2):234-58. doi: 10.1128/mr.55.2.234-258.1991.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.
J Biol Chem. 1951 Nov;193(1):265-75.
2
ADENOSINE 3',5'-PHOSPHATE IN ESCHERICHIA COLI.
J Biol Chem. 1965 Mar;240:1309-14.
3
PURIFICATION AND PROPERTIES OF RABBIT SKELETAL MUSCLE PHOSPHORYLASE B KINASE.
Biochemistry. 1964 Aug;3:1022-33. doi: 10.1021/bi00896a003.
4
Nutrition, growth, and morphogenesis of Mucor rouxii.
J Bacteriol. 1962 Oct;84(4):841-58. doi: 10.1128/jb.84.4.841-858.1962.
5
Cyclic 3', 5'-amp in Saccharomyces carlsbergensis under various conditions of catabolite repression.
FEBS Lett. 1971 Mar 5;13(3):184-186. doi: 10.1016/0014-5793(71)80231-4.
6
Comparative inductive responses of two beta-galactosidases of Neurospora.
J Bacteriol. 1967 May;93(5):1631-7. doi: 10.1128/jb.93.5.1631-1637.1967.
7
Effect of glucose on the activity and the kinetics of the maltose-uptake system and of alpha-glucosidase in Saccharomyces cerevisiae.
Biochim Biophys Acta. 1969 Jul 30;184(2):299-305. doi: 10.1016/0304-4165(69)90032-4.
8
Control of trehalase synthesis in Neurospora crassa.
Am J Bot. 1969 Nov-Dec;56(10):1160-6.
9
Influence of oxygen on maltose metabolism by Mucor rouxii.
J Gen Microbiol. 1969 Nov;59(1):13-9. doi: 10.1099/00221287-59-1-13.
10
Physiological basis of transient repression of catabolic enzymes in Escherichia coli.
J Bacteriol. 1970 May;102(2):411-22. doi: 10.1128/jb.102.2.411-422.1970.
Zotero 插件