Paryani Mukesh, Khandekar Rajiv B, Dole Kuldeep, Dharmadhikari Sheetal, Rishikeshi Nikhil
Department of Community Ophthalmology, H V Desai Eye Hospital, Hadapsar, Pune, India.
Oman J Ophthalmol. 2012 Sep;5(3):150-6. doi: 10.4103/0974-620X.106094.
We compared vision and quality of life (VQL) of children aged 5-15 years and operated for unilateral and bilateral cataract between 2008 and 2010 in western India.
In this cohort study, ophthalmologists assessed vision, anterior and posterior segment of eyes with cataract. Children completed a functional vision questionnaire (LVP-FVQ). Follow up at 6 months after surgery included the best corrected visual acuity (BCVA), FVQ and eye assessment. The improvement of BCVA and quality of life were compared in group of unilateral and bilateral cataract.
A total of 20 (70%) bilateral and 7 (39%) unilateral cataract were operated within 1 month of detection. All 48 eyes with bilateral cataract were congenital and 12 (67%) unilateral cataract were traumatic. Among bilateral group, 27 eyes [56.2% (95% confidence interval (CI) 44.4-72.2)] and in unilateral group 11 eyes [61.1% (95% CI 38.6-83.6)] had vision ≥ 20/60 at 6 months follow up. The visual gain was significantly higher in children who were operated between 1 month and 1 year of detection (adjusted Odds ratio (OR) = 15.6 P = 0.03). Positive impact on VQL in bilateral group was noted in 50%, 27%, and 13% children for subscale of distant vision, near vision, and field of vision, respectively. There was positive impact in these subscales among children with unilateral cataract. Thirty percent eyes with bilateral cataract and 22% of eyes with unilateral cataract improved their vision. Surgery within 1 month of cataract was significant predictor of improved vision (OR = 16.6 P = 0.02).
Vision and VQL improved in children with unilateral and bilateral cataract. However, it was better 6 months following surgery in children with bilateral cataract than in children with unilateral cataract.
我们比较了2008年至2010年期间在印度西部接受单侧和双侧白内障手术的5至15岁儿童的视力和生活质量（VQL）。
在这项队列研究中，眼科医生评估了白内障患儿的视力、眼睛的前段和后段。儿童完成了一份功能性视力问卷（LVP-FVQ）。术后6个月的随访包括最佳矫正视力（BCVA）、FVQ和眼部评估。比较了单侧和双侧白内障组中BCVA和生活质量的改善情况。
共有20例（70%）双侧白内障和7例（39%）单侧白内障在检测后1个月内接受了手术。所有48例双侧白内障患儿均为先天性，12例（67%）单侧白内障为外伤性。在双侧组中，27只眼[56.2%（95%置信区间（CI）44.4-72.2）]，单侧组中11只眼[61.1%（95%CI 38.6-83.6）]在随访6个月时视力≥20/60。在检测后1个月至1年接受手术的儿童中，视力提高显著更高（调整后的优势比（OR）=15.6，P=0.03）。在双侧组中，分别有50%、27%和13%的儿童在远视力、近视力和视野子量表上对VQL有积极影响。单侧白内障患儿在这些子量表上也有积极影响。30%的双侧白内障眼和22%的单侧白内障眼视力得到改善。白内障发病后1个月内进行手术是视力改善的重要预测因素（OR=16.6，P=0.02）。
单侧和双侧白内障患儿的视力和VQL均有改善。然而，双侧白内障患儿术后6个月的情况比单侧白内障患儿更好。
