采用垂直腔面发射激光光源的高精度、高准确度超长距离扫频源光相干断层扫描技术。
High-precision, high-accuracy ultralong-range swept-source optical coherence tomography using vertical cavity surface emitting laser light source.
机构信息
Department of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
出版信息
Opt Lett. 2013 Mar 1;38(5):673-5. doi: 10.1364/OL.38.000673.
Abstract
We demonstrate ultralong-range swept-source optical coherence tomography (OCT) imaging using vertical cavity surface emitting laser technology. The ability to adjust laser parameters and high-speed acquisition enables imaging ranges from a few centimeters up to meters using the same instrument. We discuss the challenges of long-range OCT imaging. In vivo human-eye imaging and optical component characterization are presented. The precision and accuracy of OCT-based measurements are assessed and are important for ocular biometry and reproducible intraocular distance measurement before cataract surgery. Additionally, meter-range measurement of fiber length and multicentimeter-range imaging are reported. 3D visualization supports a class of industrial imaging applications of OCT.
摘要
我们展示了使用垂直腔面发射激光器技术的超长距离扫频光学相干断层扫描 (OCT) 成像。通过调整激光参数和高速采集的能力，同一仪器可实现从几厘米到几米的成像范围。我们讨论了长距离 OCT 成像的挑战。本文展示了体内人眼成像和光学元件特性。评估了基于 OCT 的测量的精度和准确性，这对于白内障手术前的眼生物测量和可重复的眼内距离测量很重要。此外，还报告了光纤长度的米级测量和多厘米级的成像。3D 可视化支持 OCT 的一类工业成像应用。
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本文引用的文献
1
Rapidly swept, ultra-widely-tunable 1060 nm MEMS-VCSELs.快速扫描、超宽可调谐1060纳米微机电系统垂直腔面发射激光器
Electron Lett. 2012 Oct 11;48(21):1331-1333. doi: 10.1049/el.2012.3180.
2
Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers.使用垂直腔面发射激光器的超高速扫频源光学相干断层扫描技术进行视网膜、眼前节和全眼成像。
Biomed Opt Express. 2012 Nov 1;3(11):2733-51. doi: 10.1364/BOE.3.002733. Epub 2012 Oct 3.
3
Ultrahigh speed 1050nm swept source/Fourier domain OCT retinal and anterior segment imaging at 100,000 to 400,000 axial scans per second.超高速1050纳米扫频光源/傅里叶域光学相干断层扫描技术，每秒可进行100000至400000次轴向扫描，用于视网膜和眼前节成像。
Opt Express. 2010 Sep 13;18(19):20029-48. doi: 10.1364/OE.18.020029.
4
Eye-length measurement by interferometry with partially coherent light.使用部分相干光干涉测量法进行眼轴长度测量。
Opt Lett. 1988 Mar 1;13(3):186-8. doi: 10.1364/ol.13.000186.
5
Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway.将解剖光学相干断层扫描技术应用于下呼吸道的定量三维成像。
Opt Express. 2008 Oct 27;16(22):17521-9. doi: 10.1364/oe.16.017521.
6
Optical coherence tomography.光学相干断层扫描
Science. 1991 Nov 22;254(5035):1178-81. doi: 10.1126/science.1957169.
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