Kitsmiller Vincent J, Dummer Matthew M, Johnson Klein, Cole Garrett D, O'Sullivan Thomas D
Opt Express. 2018 Aug 6;26(16):21033-21043. doi: 10.1364/OE.26.021033.
We present an approach for performing frequency domain diffuse optical spectroscopy (fd-DOS) utilizing a near-infrared tunable vertical cavity surface emitting laser (VCSEL) that enables high spectral resolution optical sensing in a miniature format. The tunable VCSEL, designed specifically for deep tissue imaging and sensing, utilizes an electrothermally tunable microelectromechanical systems topside mirror to tune the laser cavity resonance. At room temperature, the laser is tunable across 14nm from 769 to 782nm with single mode CW output and a peak output power of 1.3mW. We show that the tunable VCSEL is suitable for use in fd-DOS by measuring the optical properties of a tissue-simulating phantom over the tunable range. Optical properties were recovered within 0.0006mm (absorption) and 0.09mm (reduced scattering) compared to a broadband fd-DOS reference system. Our results indicate that tunable VCSELs may be an attractive choice to enable high spectral resolution optical sensing in a wearable format.
我们提出了一种利用近红外可调垂直腔面发射激光器（VCSEL）进行频域漫射光学光谱（fd-DOS）的方法，该方法能够以微型形式实现高光谱分辨率光学传感。专门为深度组织成像和传感设计的可调VCSEL，利用电热可调微机电系统顶部反射镜来调谐激光腔共振。在室温下，该激光器在769至782nm范围内可调谐14nm，具有单模连续波输出，峰值输出功率为1.3mW。我们通过在可调谐范围内测量组织模拟体模的光学特性，表明可调VCSEL适用于fd-DOS。与宽带fd-DOS参考系统相比，光学特性在0.0006mm（吸收）和0.09mm（约化散射）内得到恢复。我们的结果表明，可调VCSEL可能是在可穿戴形式中实现高光谱分辨率光学传感的一个有吸引力的选择。
