Department of Mechanical Engineering, Faculty of Engineering and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
J Biomech. 2013 Apr 26;46(7):1335-42. doi: 10.1016/j.jbiomech.2013.02.002. Epub 2013 Mar 8.
One treatment method for aortic aneurysm is the invasive insertion of a stent into the aneurysm. Another method is wrapping the aneurysm using newly developed expanded polytetrafluoroethylene (PTFE) material. A virtual stented aneurysm model and a wrapped aneurysm model were created to study the flow and wall dynamics by means of fluid-structure interaction analyses. The flow velocity and pressure distribution as well as the deformation and wall stress were investigated. Stenting significantly changed the blood flow pattern and the vortexes in the aneurysm. Wrapping increased the thickness of the aneurysm wall and increased the strength of the vessel wall. The maximum von Mises stress in the stented model was found to be 220,494 Pa and 228,218 Pa at the time of peak flow and peak pressure, respectively. This was reduced by 37.8% and 36.7% to 137,200 and 144,354 Pa, respectively, in the wrapped model. Our results provide information that may improve the understanding of the biomechanics of stenting and wrapping.
一种治疗主动脉瘤的方法是将支架侵入性地插入动脉瘤中。另一种方法是使用新开发的膨体聚四氟乙烯(PTFE)材料包裹动脉瘤。创建了一个虚拟支架动脉瘤模型和一个包裹动脉瘤模型,通过流固耦合分析研究流动和壁动力学。研究了流速和压力分布以及变形和壁应力。支架置入显著改变了动脉瘤中的血流模式和涡流。包裹增加了动脉瘤壁的厚度并增加了血管壁的强度。在峰值流量和峰值压力时,支架模型中的最大 von Mises 应力分别为 220494Pa 和 228218Pa,在包裹模型中分别降低了 37.8%和 36.7%,至 137200Pa 和 144354Pa。我们的结果提供了可能有助于理解支架置入和包裹的生物力学的信息。