• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Antiproliferative activity of hexane extract from Tunisian Cistus libanotis, Cistus monspeliensis and Cistus villosus.突尼斯岩蔷薇、蒙氏岩蔷薇和毛叶岩蔷薇正己烷提取物的抗增殖活性。
Chem Cent J. 2013 Mar 5;7(1):47. doi: 10.1186/1752-153X-7-47.
2
Antioxidant activity and chemical composition of three Tunisian Cistus: Cistus monspeliensis, Cistus villosus and Cistus libanotis.三种突尼斯 Cistus 的抗氧化活性和化学成分：Cistus monspeliensis、Cistus villosus 和 Cistus libanotis。
Nat Prod Res. 2015 Feb;29(3):223-30. doi: 10.1080/14786419.2014.947486. Epub 2014 Aug 12.
3
Chemistry and functional properties in prevention of neurodegenerative disorders of five Cistus species essential oils.五种岩蔷薇属植物精油在预防神经退行性疾病中的化学和功能特性。
Food Chem Toxicol. 2013 Sep;59:586-94. doi: 10.1016/j.fct.2013.06.040. Epub 2013 Jul 2.
4
A systematic study of the polyphenolic composition of aqueous extracts deriving from several Cistus genus species: evolutionary relationship.对源自多个Cistus 属物种的水提物的多酚组成进行系统研究：进化关系。
Phytochem Anal. 2011 Jul-Aug;22(4):303-12. doi: 10.1002/pca.1281. Epub 2011 Jan 24.
5
Biological activities and determination of the mode of action of Tunisian and ethanolic extracts.突尼斯和乙醇提取物的生物活性及作用方式的测定。
Int J Environ Health Res. 2024 Jan;34(1):127-137. doi: 10.1080/09603123.2022.2133096. Epub 2022 Oct 15.
6
Antibacterial and antifungal activities of Cistus incanus and C. monspeliensis leaf extracts.白苞岩蔷薇和蒙氏岩蔷薇叶提取物的抗菌和抗真菌活性。
Therapie. 1999 Nov-Dec;54(6):731-3.
7
Phytochemical study of Cistus libanotis L.乳香黄连木的植物化学研究
Nat Prod Res. 2015;29(2):189-92. doi: 10.1080/14786419.2014.968569. Epub 2014 Oct 14.
8
Antimicrobial activities of the leaf extracts of two Moroccan Cistus L. species.两种摩洛哥岩蔷薇属植物叶片提取物的抗菌活性。
J Ethnopharmacol. 2006 Mar 8;104(1-2):104-7. doi: 10.1016/j.jep.2005.08.062. Epub 2005 Oct 6.
9
Essential oils and hexane extracts from leaves and fruits of Cistus monspeliensis. Cytotoxic activity of ent-13-epi-manoyl oxide and its isomers.蒙氏岩蔷薇叶和果实中的精油及己烷提取物。对映-13-表-氧化玫瑰呋喃及其异构体的细胞毒性活性。
Planta Med. 2001 Mar;67(2):168-71. doi: 10.1055/s-2001-11497.
10
Antiproliferative and cytotoxic activity of extracts from Cistus incanus L. and Cistus monspeliensis L. on human prostate cell lines.白花丹和马缨丹提取物对人前列腺细胞系的抗增殖和细胞毒性作用。
Nat Prod Res. 2011 Feb;25(3):188-202. doi: 10.1080/14786410802583148.

引用本文的文献

1
Biology, Antioxidant Activity, and Therapeutic Potential of sp.-A Comprehensive Review.某属生物、抗氧化活性及治疗潜力——全面综述
Int J Mol Sci. 2025 Jul 3;26(13):6400. doi: 10.3390/ijms26136400.
2
Phytochemical Profile and In Vitro Cytotoxic, Genotoxic, and Antigenotoxic Evaluation of L. Leaf Extract.L. 叶提取物的植物化学特征及体外细胞毒性、遗传毒性和抗遗传毒性评价
Int J Mol Sci. 2024 Dec 22;25(24):13707. doi: 10.3390/ijms252413707.
3
Characterising the Metabolomic Diversity and Biological Potentials of Extracts from Different Parts of Two Species Using UHPLC-MS/MS and In Vitro Techniques.使用超高效液相色谱-串联质谱法（UHPLC-MS/MS）和体外技术表征两种植物不同部位提取物的代谢组学多样性和生物学潜力。
Pathogens. 2024 Sep 13;13(9):795. doi: 10.3390/pathogens13090795.
4
Mediterranean Shrub Species as a Source of Biomolecules against Neurodegenerative Diseases.地中海灌木物种作为神经退行性疾病生物分子的来源。
Molecules. 2023 Dec 16;28(24):8133. doi: 10.3390/molecules28248133.
5
Molecular Characterization of Gene-Mediated Resistance and Susceptibility of ESKAPE Clinical Isolates to L. and L. Extracts.基因介导的ESKAPE临床分离株对L.和L.提取物的抗性和敏感性的分子特征分析
Evid Based Complement Alternat Med. 2022 Sep 27;2022:7467279. doi: 10.1155/2022/7467279. eCollection 2022.
6
Essential Oils Derived from Species Activate Mitochondria by Inducing SIRT1 Expression in Human Keratinocytes, Leading to Senescence Inhibition.从 物种中提取的精油通过诱导人角质形成细胞中的 SIRT1 表达来激活线粒体，从而抑制衰老。
Molecules. 2022 Mar 22;27(7):2053. doi: 10.3390/molecules27072053.
7
A Review on sp.: Phytochemical and Antimicrobial Activities.关于[物种名称]的综述：植物化学成分与抗菌活性。 （注：原文中“sp.”一般指物种，这里因未明确具体物种名称，翻译时保留英文表述并用方括号标注）
Plants (Basel). 2021 Jun 15;10(6):1214. doi: 10.3390/plants10061214.
8
Characterization of × L. and L. Extracts as Potential Multifunctional Antioxidant Ingredients for Skin Protecting Cosmetics.×L.和L.提取物作为用于皮肤保护化妆品的潜在多功能抗氧化成分的特性研究
Antioxidants (Basel). 2020 Mar 1;9(3):202. doi: 10.3390/antiox9030202.
9
Bioavailable Citrus sinensis Extract: Polyphenolic Composition and Biological Activity.生物可利用的甜橙提取物：多酚组成与生物活性。
Molecules. 2017 Apr 15;22(4):623. doi: 10.3390/molecules22040623.
10
Genus Cistus: a model for exploring labdane-type diterpenes' biosynthesis and a natural source of high value products with biological, aromatic, and pharmacological properties.乳香树属（Cistus）：探索拉伯烷型二萜生物合成的模型植物，也是具有生物、芳香和药理特性的高价值产品的天然来源。
Front Chem. 2014 Jun 11;2:35. doi: 10.3389/fchem.2014.00035. eCollection 2014.

本文引用的文献

1
Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2.黄曲霉毒素 B1 和 B2 及其代谢物 M1 和 M2 对巨噬细胞活性的调节。
Toxicon. 2012 May;59(6):644-50. doi: 10.1016/j.toxicon.2012.02.010. Epub 2012 Mar 3.
2
Vitamins C and E: beneficial effects from a mechanistic perspective.维生素 C 和 E：从机制角度看有益作用。
Free Radic Biol Med. 2011 Sep 1;51(5):1000-13. doi: 10.1016/j.freeradbiomed.2011.05.017. Epub 2011 May 25.
3
A systematic study of the polyphenolic composition of aqueous extracts deriving from several Cistus genus species: evolutionary relationship.对源自多个Cistus 属物种的水提物的多酚组成进行系统研究：进化关系。
Phytochem Anal. 2011 Jul-Aug;22(4):303-12. doi: 10.1002/pca.1281. Epub 2011 Jan 24.
4
Cistaceae aqueous extracts containing ellagitannins show antioxidant and antimicrobial capacity, and cytotoxic activity against human cancer cells.含鞣花单宁的安息香科水提取物具有抗氧化和抗菌能力，并对人类癌细胞具有细胞毒性活性。
Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2273-82. doi: 10.1016/j.fct.2010.05.060. Epub 2010 May 25.
5
Dietary intakes of omega-6 and omega-3 polyunsaturated fatty acids and the risk of breast cancer.ω-6和ω-3多不饱和脂肪酸的膳食摄入量与乳腺癌风险
Int J Cancer. 2009 Feb 15;124(4):924-31. doi: 10.1002/ijc.23980.
6
The role of herbs and spices in cancer prevention.草药和香料在癌症预防中的作用。
J Nutr Biochem. 2008 Jun;19(6):347-61. doi: 10.1016/j.jnutbio.2007.11.003.
7
Simultaneous determination of catechins, rutin, and gallic acid in Cistus species extracts by HPLC with diode array detection.采用高效液相色谱-二极管阵列检测法同时测定岩蔷薇属植物提取物中的儿茶素、芦丁和没食子酸。
J Chromatogr Sci. 2008 Feb;46(2):150-6. doi: 10.1093/chromsci/46.2.150.
8
Flavonoids with anti-inflammatory and antinociceptive activity from Cistus laurifolius L. leaves through bioassay-guided procedures.通过生物测定指导程序从月桂岩蔷薇叶中分离具有抗炎和抗伤害感受活性的黄酮类化合物。
J Ethnopharmacol. 2007 Jul 25;112(3):524-30. doi: 10.1016/j.jep.2007.04.011. Epub 2007 Apr 25.
9
Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells.橄榄油中的苦味成分可逆转HER2过表达乳腺癌细胞对曲妥珠单抗（赫赛汀）产生的获得性自身耐药性。
BMC Cancer. 2007 May 9;7:80. doi: 10.1186/1471-2407-7-80.
10
Separations of flavan-3-ols and dimeric proanthocyanidins by capillary electrophoresis.通过毛细管电泳分离黄烷-3-醇和二聚体原花青素。
Planta Med. 1998 Feb;64(1):63-7. doi: 10.1055/s-2006-957368.

突尼斯岩蔷薇、蒙氏岩蔷薇和毛叶岩蔷薇正己烷提取物的抗增殖活性。

Antiproliferative activity of hexane extract from Tunisian Cistus libanotis, Cistus monspeliensis and Cistus villosus.

作者信息

Ben Jemia Mariem, Kchouk Mohamed Elyes, Senatore Felice, Autore Giuseppina, Marzocco Stefania, De Feo Vincenzo, Bruno Maurizio

机构信息

Department of Pharmacy, University of Salerno, via Ponte Don Melillo, 84084, Fisciano (Salerno), Italy.

出版信息

Chem Cent J. 2013 Mar 5;7(1):47. doi: 10.1186/1752-153X-7-47.

DOI:10.1186/1752-153X-7-47
PMID:23497569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3599238/
Abstract

BACKGROUND

As a part of our investigation on Tunisian medicinal plants, we have carried out a phytochemical investigation of the hexane extracts from leaves of Cistus libanotis, C. villosus and C. monspeliensis, evualuating also their possible antiproliferative activity in vitro.

RESULTS

The major compounds of hexane extracts were identified and quantified by GC-MS. The composition of the three species, although belonging to the same genus, is completely different. The antiproliferative activity was evaluated against murine monocyte/macrophages (J774.A1), human melanoma cells (A-375), and human breast cancer cells (MCF-7), showing major activity against the human melanoma cell line A-375.

CONCLUSIONS

The chemical composition of the hexane extracts from the three Cistus species can be useful in the chemosystematics of this complex genus. The preliminary antiproliferative activity against human melanoma cell line A-375 deserve further investigations in order to determine the compounds, or their combinations, which are the main responsible for the antiproliferative activity and its possible mechanism(s) of action.

摘要

背景

作为我们对突尼斯药用植物研究的一部分，我们对乳香黄连木、毛黄连木和蒙斯佩利黄连木叶的己烷提取物进行了植物化学研究，并评估了它们在体外可能的抗增殖活性。

结果

通过气相色谱 - 质谱联用（GC-MS）对己烷提取物的主要化合物进行了鉴定和定量。这三个物种虽然属于同一属，但其成分完全不同。对鼠单核细胞/巨噬细胞（J774.A1）、人黑色素瘤细胞（A - 375）和人乳腺癌细胞（MCF - 7）进行了抗增殖活性评估，结果显示对人黑色素瘤细胞系A - 375具有主要活性。

结论

这三种黄连木属植物己烷提取物的化学成分有助于该复杂属的化学分类学研究。针对人黑色素瘤细胞系A - 375的初步抗增殖活性值得进一步研究，以确定对抗增殖活性及其可能作用机制起主要作用的化合物或其组合。