Tomoda M, Shimizu N, Gonda R, Kanari M, Yamada H, Hikino H
Kyoritsu College of Pharmacy, Tokyo, Japan.
Planta Med. 1990 Apr;56(2):168-70. doi: 10.1055/s-2006-960917.
Seven polysaccharides and peptidoglycans obtained from the seeds of Malva verticillata were tested for anti-complementary activity. Remarkable activities were observed for MVS-I and MVS-IIA. The former is mainly composed of beta-1,3-linked D-glucan and of alpha-1,5-linked L-arabino-beta-3,6-branched D-galactan, and the latter is essentially alpha-1,5-linked L-arabino-beta-3,6-branched D-galactan. Further, considerable activities were observed for MVS-IIIA and MVS-IVA. Both glycans possess arabino-3,6-galactan moieties accompanying alpha-1,3-linked L-arabinopyranosyl, beta-1,4-linked D-xylosyl, and alpha-1,4-linked D-galacturonic acid units. In addition, the major neutral polysaccharide (MVS-I), the major peptidoglycan (MVS-V), and the polysaccharide-rich fraction (MVS-V-CH) obtained from MVS-V were tested for hypoglycemic activity. MVS-I especially showed remarkable activity, and MVS-V-CH also exhibited significant activity. From the viewpoint of structural features, the latter belongs to pectic substances.
对从冬葵种子中获得的七种多糖和肽聚糖进行了抗补体活性测试。观察到MVS-I和MVS-IIA具有显著活性。前者主要由β-1,3-连接的D-葡聚糖和α-1,5-连接的L-阿拉伯糖基-β-3,6-分支的D-半乳聚糖组成，后者主要是α-1,5-连接的L-阿拉伯糖基-β-3,6-分支的D-半乳聚糖。此外，还观察到MVS-IIIA和MVS-IVA具有相当的活性。这两种聚糖都含有阿拉伯糖-3,6-半乳聚糖部分，同时伴有α-1,3-连接的L-阿拉伯吡喃糖基、β-1,4-连接的D-木糖基和α-1,4-连接的D-半乳糖醛酸单元。此外，还对从MVS-V中获得的主要中性多糖（MVS-I）、主要肽聚糖（MVS-V）和富含多糖的组分（MVS-V-CH）进行了降血糖活性测试。MVS-I尤其表现出显著活性，MVS-V-CH也表现出显著活性。从结构特征来看，后者属于果胶物质。
