Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
J Pain. 2013 May;14(5):492-501. doi: 10.1016/j.jpain.2012.12.019. Epub 2013 Mar 26.
A recent randomized multisite clinical trial found that cognitive-behavioral therapy (CBT) was significantly more effective than fibromyalgia education (FE) in reducing functional disability in adolescents with juvenile fibromyalgia (JFM). The primary objective of this study was to examine the psychological processes of CBT effectiveness by evaluating changes in pain coping, catastrophizing, and coping efficacy and to test these changes as mediators of continued improvements in functional disability and depressive symptoms at 6-month follow-up. One hundred adolescents (11-18 years old) with JFM completed the clinical trial. Coping, catastrophizing, and coping efficacy (Pain Coping Questionnaire) and the outcomes of functional disability (Functional Disability Inventory) and depressive symptoms (Children's Depression Inventory) were measured at baseline, posttreatment, and 6-month follow-up. Participants in both conditions showed significant improvement in coping, catastrophizing, and efficacy by the end of the study, but significantly greater improvements were found immediately following treatment for those who received CBT. Treatment gains were maintained at follow-up. Baseline to posttreatment changes in coping, catastrophizing, and efficacy were not found to mediate improvements in functional disability or depressive symptoms from posttreatment to follow-up. Future directions for understanding mechanisms of CBT effectiveness in adolescents with chronic pain are discussed.
CBT led to significant improvements in pain coping, catastrophizing, and efficacy that were sustained over time in adolescents with juvenile fibromyalgia. Clinicians treating adolescents with JFM should focus on teaching a variety of adaptive coping strategies to help patients simultaneously regain functioning and improve mood.
最近一项随机多地点临床试验发现,认知行为疗法(CBT)在减少青少年纤维肌痛(JFM)患者的功能障碍方面明显优于纤维肌痛教育(FE)。本研究的主要目的是通过评估疼痛应对、灾难化和应对效能的变化来检验 CBT 有效性的心理过程,并测试这些变化是否作为功能障碍和抑郁症状持续改善的中介因素在 6 个月随访时出现。100 名患有 JFM 的青少年(11-18 岁)完成了临床试验。在基线、治疗后和 6 个月随访时测量了应对、灾难化和应对效能(疼痛应对问卷)以及功能障碍(功能障碍量表)和抑郁症状(儿童抑郁量表)的结果。两种情况下的参与者在研究结束时在应对、灾难化和效能方面都有显著改善,但接受 CBT 的参与者在治疗后立即发现有更大的改善。治疗效果在随访时得以维持。从基线到治疗后的应对、灾难化和效能变化与从治疗后到随访时的功能障碍或抑郁症状的改善无关。讨论了理解青少年慢性疼痛中 CBT 有效性机制的未来方向。
CBT 导致青少年纤维肌痛患者的疼痛应对、灾难化和效能显著改善,并随着时间的推移得以维持。治疗 JFM 青少年的临床医生应专注于教授各种适应性应对策略,帮助患者同时恢复功能和改善情绪。