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中国沿海与内陆省份糖尿病患病率及知晓率的地区差异:一项基于人群的横断面研究

Regional differences in diabetes prevalence and awareness between coastal and interior provinces in China: a population-based cross-sectional study.

作者信息

Xu Shaoyong, Ming Jie, Xing Ying, Gao Bin, Yang Chunbao, Ji Qiuhe, Chen Gang

机构信息

Department of Endocrinology, First Affiliated Hospital of Fourth Military Medical University, 169 Changle Road West, Xi'an, China.

出版信息

BMC Public Health. 2013 Apr 4;13:299. doi: 10.1186/1471-2458-13-299.

Abstract

BACKGROUND

Most studies on diabetes prevalence and awareness in China are regional or about a single province, and differences between coastal and interior provinces have not been discussed even in the nation-based studies. The aim of this study was to determine regional differences in diabetes prevalence and awareness between coastal and interior provinces, and to identify the factors associated with diabetes prevalence and awareness.

METHODS

Provinces Fujian and Shaanxi were chosen to represent the coastal and interior provinces, respectively. The data of two provinces were from the China National Diabetes and Metabolic Disorders Study 2007-08. A total of 5926 people (Fujian 2672 and Shaanxi 3254) aged above 20 years were included as participants in the study. Age-standardized prevalence and awareness were compared between provinces. Logistic regression analysis was performed not only to examine risk factors of diabetes prevalence and awareness, but also to examine the association between regional difference and diabetes prevalence and awareness.

RESULTS

The age-standardized prevalence of diabetes in Fujian was higher than that in Shaanxi among total (11.5% vs. 8.0%), male (13.6% vs. 8.9%) and female (10.8% vs. 7.4%) populations. Diabetes awareness for total and male population in Fujian was higher than that in Shaanxi (42.3% vs. 34.9% and 46.8% vs. 35.2%, respectively). Age, sex, central obesity, family history of diabetes, and metabolic risk factors were all significantly associated with diabetes prevalence in both provinces. However, cigarette smoking was significantly associated with prevalence in Fujian and physical activity was significantly associated with the prevalence in Shaanxi. Family history of diabetes was the only independent risk factor of diabetes awareness in both provinces. After being adjusted for all listed risk factors, the regional difference of diabetes prevalence was still significant, but that of diabetes awareness lost significance.

CONCLUSIONS

Both diabetes prevalence and awareness were higher in coastal provinces and lower in interior provinces in China. Lifestyle risk factors were found to contribute differently to diabetes prevalence in the two provinces and other unknown risk factors may account for differences of diabetes prevalence between provinces. In addition, family history of diabetes was the only independent risk factor in both provinces.

摘要

背景

中国大多数关于糖尿病患病率及知晓率的研究都是区域性的或仅涉及单个省份,即使是基于全国范围的研究也未探讨沿海省份与内陆省份之间的差异。本研究旨在确定沿海省份与内陆省份在糖尿病患病率及知晓率方面的区域差异,并找出与糖尿病患病率及知晓率相关的因素。

方法

分别选取福建省和陕西省代表沿海省份和内陆省份。两省的数据均来自2007 - 2008年中国国家糖尿病和代谢紊乱研究。共有5926名年龄在20岁以上的人(福建2672人,陕西3254人)纳入本研究作为参与者。比较两省年龄标准化后的患病率及知晓率。进行逻辑回归分析,不仅用于检验糖尿病患病率及知晓率的危险因素,还用于检验区域差异与糖尿病患病率及知晓率之间的关联。

结果

在总体人群(11.5%对8.0%)、男性人群(13.6%对8.9%)和女性人群(10.8%对7.4%)中,福建省年龄标准化后的糖尿病患病率均高于陕西省。福建省总体人群和男性人群的糖尿病知晓率高于陕西省(分别为42.3%对34.9%和46.8%对35.2%)。年龄、性别、中心性肥胖、糖尿病家族史和代谢危险因素在两省均与糖尿病患病率显著相关。然而,吸烟与福建省的患病率显著相关,体力活动与陕西省的患病率显著相关。糖尿病家族史是两省糖尿病知晓率的唯一独立危险因素。在对所有列出的危险因素进行调整后,糖尿病患病率的区域差异仍然显著,但糖尿病知晓率的区域差异不再显著。

结论

中国沿海省份的糖尿病患病率和知晓率均高于内陆省份。发现生活方式危险因素对两省糖尿病患病率的影响不同,其他未知危险因素可能导致两省糖尿病患病率存在差异。此外,糖尿病家族史是两省唯一的独立危险因素。

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