Institute of Image Processing and Pattern Recognition, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, China.
Med Phys. 2013 Apr;40(4):041910. doi: 10.1118/1.4794474.
Presence of metal artifacts is a major reason of degradation of computed tomography image quality and there is still no standard solution to this issue. A class of recently investigated metal artifact reduction (MAR) methods based on forward projection of a prior image that is artifact-free to replace the metal affected projection data have shown promising results. However, usually it is hard to get a good prior image which is close to the true image without artifacts. This work aims at creating a good prior image so that the forward projection can replace the metal affected projection data well.
The proposed method consists of four steps based on the forward projection MAR framework. First, metal implants in the reconstructed image are segmented and the corresponding metal traces in the projection domain are identified. Then the prior image is obtained by two steps. A processed precorrected image is generated as an initial prior image first and then in the next step it is used as the initial image of the iterative reconstruction from the unaffected projection data to generate a better prior image. In order to deal with severe artifacts, the iteration incorporates the total variation minimization constraint as well as a novel constraint which forces the soft tissue region near metal to be as flat as possible. Finally, the projection is completed using forward projection of the prior image and the corrected image is reconstructed by FBP. A linear interpolation MAR method and two recently reported forward projection based methods are performed simultaneously for comparison.
The proposed method shows outstanding performance on both phantoms' and patients' datasets. This approach can reduce artifacts dramatically and restore tissue structures near metal to a large extent. Unlike competing MAR methods, it can effectively prevent introduction of new artifacts and false structures. Moreover, the proposed method has the lowest RMSE in regions of both soft tissue and bone tissue among the corrected images and is ranked as the best method for evaluation, by radiologists.
Both subjective and quantitative evaluations of the results demonstrate the superior performance of the proposed algorithm, compared to that of the competing methods. This method offers a remarkable improvement of the image quality.
金属伪影的存在是降低计算机断层扫描图像质量的一个主要原因,目前仍没有对此问题的标准解决方案。最近研究的一类基于对无伪影的先验图像进行正向投影来替代受金属影响的投影数据的金属伪影减少(MAR)方法已经显示出了有前景的结果。然而,通常很难获得一个没有伪影的接近真实图像的良好先验图像。这项工作旨在创建一个良好的先验图像,以便正向投影能够很好地替代受金属影响的投影数据。
所提出的方法基于正向投影 MAR 框架由四个步骤组成。首先,在重建图像中分割金属植入物,并识别投影域中的相应金属痕迹。然后通过两步获得先验图像。首先生成经过预处理的校正图像作为初始先验图像,然后在下一个步骤中,将其用作不受影响的投影数据迭代重建的初始图像,以生成更好的先验图像。为了处理严重的伪影,迭代包括总变差最小化约束以及一个新的约束,该约束迫使金属附近的软组织区域尽可能平坦。最后,使用先验图像的正向投影完成投影,并通过 FBP 重建校正图像。同时进行线性插值 MAR 方法和两种最近报道的基于正向投影的方法进行比较。
该方法在体模和患者数据集上均表现出出色的性能。该方法可以显著减少伪影,并在很大程度上恢复金属附近的组织结构。与竞争的 MAR 方法不同,它可以有效地防止引入新的伪影和虚假结构。此外,在所校正图像的软组织和骨组织区域中,该方法的 RMSE 最低,并且在放射科医生的评估中被评为最佳方法。
与竞争方法相比,对结果的主观和定量评估都表明了所提出算法的卓越性能。该方法显著提高了图像质量。