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计算机断层扫描中的归一化金属伪影减少(NMAR)。

Normalized metal artifact reduction (NMAR) in computed tomography.

机构信息

Institute of Medical Physics, University of Erlangen-Nürnberg, D-91052 Erlangen, Germany.

出版信息

Med Phys. 2010 Oct;37(10):5482-93. doi: 10.1118/1.3484090.

Abstract

PURPOSE

While modern clinical CT scanners under normal circumstances produce high quality images, severe artifacts degrade the image quality and the diagnostic value if metal prostheses or other metal objects are present in the field of measurement. Standard methods for metal artifact reduction (MAR) replace those parts of the projection data that are affected by metal (the so-called metal trace or metal shadow) by interpolation. However, while sinogram interpolation methods efficiently remove metal artifacts, new artifacts are often introduced, as interpolation cannot completely recover the information from the metal trace. The purpose of this work is to introduce a generalized normalization technique for MAR, allowing for efficient reduction of metal artifacts while adding almost no new ones. The method presented is compared to a standard MAR method, as well as MAR using simple length normalization.

METHODS

In the first step, metal is segmented in the image domain by thresholding. A 3D forward projection identifies the metal trace in the original projections. Before interpolation, the projections are normalized based on a 3D forward projection of a prior image. This prior image is obtained, for example, by a multithreshold segmentation of the initial image. The original rawdata are divided by the projection data of the prior image and, after interpolation, denormalized again. Simulations and measurements are performed to compare normalized metal artifact reduction (NMAR) to standard MAR with linear interpolation and MAR based on simple length normalization.

RESULTS

Promising results for clinical spiral cone-beam data are presented in this work. Included are patients with hip prostheses, dental fillings, and spine fixation, which were scanned at pitch values ranging from 0.9 to 3.2. Image quality is improved considerably, particularly for metal implants within bone structures or in their proximity. The improvements are evaluated by comparing profiles through images and sinograms for the different methods and by inspecting ROIs. NMAR outperforms both other methods in all cases. It reduces metal artifacts to a minimum, even close to metal regions. Even for patients with dental fillings, which cause most severe artifacts, satisfactory results are obtained with NMAR. In contrast to other methods, NMAR prevents the usual blurring of structures close to metal implants if the metal artifacts are moderate.

CONCLUSIONS

NMAR clearly outperforms the other methods for both moderate and severe artifacts. The proposed method reliably reduces metal artifacts from simulated as well as from clinical CT data. Computationally efficient and inexpensive compared to iterative methods, NMAR can be used as an additional step in any conventional sinogram inpainting-based MAR method.

摘要

目的

虽然现代临床 CT 扫描仪在正常情况下能产生高质量的图像,但如果在测量场中有金属假体或其他金属物体,严重的伪影会降低图像质量和诊断价值。金属伪影降低(MAR)的标准方法通过内插来替换受金属影响的投影数据部分(所谓的金属痕迹或金属阴影)。然而,虽然正弦图内插方法有效地消除了金属伪影,但新的伪影经常会出现,因为内插不能完全从金属痕迹中恢复信息。本工作的目的是引入一种 MAR 的广义归一化技术,在几乎不引入新伪影的情况下,有效地减少金属伪影。所提出的方法与标准 MAR 方法以及基于简单长度归一化的 MAR 方法进行了比较。

方法

在第一步中,通过阈值处理在图像域中分割金属。三维正向投影确定原始投影中的金属痕迹。在插值之前,根据先前图像的三维正向投影对投影进行归一化。该先验图像例如可以通过初始图像的多阈值分割获得。原始 rawdata 除以先验图像的投影数据,并在插值后再次进行归一化。进行模拟和测量以比较归一化金属伪影减少(NMAR)与具有线性内插的标准 MAR 以及基于简单长度归一化的 MAR。

结果

本工作呈现了临床螺旋锥形束数据的有希望的结果。包括髋关节假体、牙填充物和脊柱固定患者,这些患者在螺距值为 0.9 至 3.2 之间进行了扫描。图像质量得到了显著改善,特别是对于骨骼结构内或其附近的金属植入物。通过比较不同方法的图像和正弦图的轮廓以及检查 ROI 来评估改进。NMAR 在所有情况下都优于其他两种方法。它将金属伪影减少到最低限度,即使在靠近金属区域的情况下也是如此。即使对于牙填充物患者,NMAR 也能获得令人满意的结果,这些患者会导致最严重的伪影。与其他方法不同,如果金属伪影中等,NMAR 可以防止靠近金属植入物的结构通常的模糊。

结论

NMAR 明显优于其他两种方法,无论是中度还是重度伪影。该方法可靠地减少了模拟和临床 CT 数据中的金属伪影。与迭代方法相比,NMAR 计算效率高且成本低,可作为任何基于常规正弦图内插的 MAR 方法的附加步骤。

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