Division of General Pediatrics, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Clin Transl Sci. 2013 Apr;6(2):88-93. doi: 10.1111/cts.12019. Epub 2013 Jan 14.
In the United States, levels of public participation in medical research in the era of Clinical and Translational Science Awards (CTSAs) are unknown.
In 2011, a household survey was administered to a sample of U.S. adults, asking whether they (and children <18 years old) had participated, or were aware of opportunities to participate, in medical research. Respondents living within 100 miles of CTSA sites were identified. Regression analyses of participation and awareness (PA) were performed, applying sampling weights to permit nationally representative inferences.
Overall, 2,150 individuals responded (completion rate = 60%); 65% of adults and 63% of families with children resided within 100 miles of ≥1 CTSA location. Research participation rates were 11% among adults and 5% among children. Among nonparticipants, awareness rates were 64% among adults and 12% among parents of children. PA among adults was associated with higher income and education, older age, presence of chronic conditions, and living within 100 miles of four specific CTSA locations. For children, PA was associated with higher household income and parents' chronic health conditions.
PA of medical research opportunities is substantially higher for adults than children. Higher PA levels near specific CTSAs merit investigation to identify their successful approaches.
在美国，临床与转化科学奖（CTSAs）时代公众参与医学研究的程度尚不清楚。
2011 年，对美国成年人进行了一项家庭调查，询问他们（和 18 岁以下的儿童）是否参与过或有机会参与医学研究。确定了居住在 CTSA 地点 100 英里范围内的受访者。对参与度和知晓度（PA）进行了回归分析，并对样本进行了加权处理，以实现全国代表性推断。
总体而言，有 2150 人（完成率为 60%）做出了回应；65%的成年人和 63%的有孩子的家庭居住在 100 英里范围内至少有一个 CTSA 地点。成年人的研究参与率为 11%，儿童为 5%。在未参与者中，成年人的知晓率为 64%，儿童父母的知晓率为 12%。成年人的 PA 与较高的收入和教育水平、较年长、存在慢性疾病以及居住在四个特定 CTSA 地点 100 英里范围内有关。对于儿童，PA 与家庭收入较高和父母的慢性健康状况有关。
与儿童相比，成年人对医学研究机会的参与度明显更高。在特定 CTSA 附近较高的 PA 水平值得进一步研究，以确定其成功方法。
