Fang Zhi-Jia, Zhang Jenny Y, He Wei-Min
Department of Radiology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.
Int J Ophthalmol. 2013 Apr 18;6(2):146-9. doi: 10.3980/j.issn.2222-3959.2013.02.07. Print 2013.
: To investigate computed tomography (CT) features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy (TAO).
A total of 605 eyes of 325 patients with exophthalmos due to TAO were classified as grade I (mild exophthalmos) or II (severe exophthalmos) based on orbital CT imaging. The increased orbital volume features, such as changes from extraocular muscles, orbital fat, or both, were analyzed.
A total of 605 eyes were analyzed, among them 62.98% presented grade I exophthalmos, while 36.02% showed grade II exophthalmos. In grade I, 56.69% showed orbital fat change, and in grade II, 89.29% exhibited extraocular muscle enlargement.
Orbital fat and extraocular muscle enlargement are likely to be observed on CTs of subjects with mild and severe exophthalmos, respectively. Our results suggest that CT findings may guide TAO clinical therapy recommendations and prognosis.
探讨中国甲状腺相关性眼病(TAO)患者眼球突出的计算机断层扫描(CT)特征。
基于眼眶CT成像,将325例因TAO导致眼球突出的患者的605只眼睛分为I级(轻度眼球突出)或II级(重度眼球突出)。分析眼眶容积增加的特征,如眼外肌、眼眶脂肪或两者的变化。
共分析605只眼睛,其中62.98%为I级眼球突出,36.02%为II级眼球突出。I级中,56.69%显示眼眶脂肪改变,II级中,89.29%表现为眼外肌增大。
在轻度和重度眼球突出患者的CT上分别可能观察到眼眶脂肪和眼外肌增大。我们的结果表明,CT表现可能指导TAO的临床治疗建议和预后。