Department of Ophthalmology, Ludwig-Maximilians-University, Klinikum der Universität München, Campus Innenstadt, Mathildenstraße 8, 80336, Munich, Germany.
Institute of Medical Statistics and Computational Biology, Faculty of Medicine, University of Cologne, Cologne, Germany.
Sci Rep. 2022 Jul 13;12(1):11973. doi: 10.1038/s41598-022-16131-4.
To determine protrusion assessment via Hertel exophthalmometry in comparison to measurement on Computed Tomography (CT). Retrospective blinded comparison of exophthalmos measurements on axial CT with Hertel exophthalmometry measurements in 113 patients. Descriptive statistics, Pearson's correlation, Kruskal-Wallis and Mann-Whitney-U test were employed for analysis. Mean difference of proptosis between both eyes was 2.4 (SD ± 2.0) mm in CT and 2.2 (SD ± 2.0) mm in Hertel measurements. Proptosis of 0-2 mm was present in 69 (61.1%), and > 2 mm in 42 (38.9%) patients in Hertel measurements (CT 64 (56.6%), and 49 (43.4%) patients). Pearson's coefficient showed a correlation of 0.793 between both methods (p < 0.001). Accuracy of Hertel measurement depended significantly from the examiners' experience (< 5 (group 1), 5-15 (2) and > 25 (3) years, p = 0.042, Kruskal-Wallis analysis; p = 0.086 group 1 vs. 2, p = 0.014 group 1 vs. 3, p = 0.688 group 2 vs. 3, Mann-Whitney-U-test), reflected by levels of Pearson's coefficient (correlation of both methods 0.691 (group 1), 0.837 (2) and 0.831 (3), respectively, p = 0.01). Generally, Hertel exophthalmometry correlates well with CT measurements. Subgroup analysis confirmed a superior quality of Hertel measurements in favour of experienced examiners. Teaching of accurate Hertel exophthalmometry should be improved. Assessment of exophthalmos using standardized criteria should be implemented for imaging reports.
通过 Hertel 突眼计与计算机断层扫描 (CT) 比较来确定突眼评估。对 113 例患者的轴向 CT 上的突眼测量值与 Hertel 突眼计测量值进行回顾性盲法比较。采用描述性统计、Pearson 相关、Kruskal-Wallis 和 Mann-Whitney-U 检验进行分析。双眼之间的平均差异为 2.4 (SD ± 2.0) mm CT 和 Hertel 测量值 2.2 (SD ± 2.0) mm。Hertel 测量值中,0-2 mm 存在 69 例 (61.1%),> 2 mm 存在 42 例 (38.9%)患者 (CT 中 64 例 (56.6%),49 例 (43.4%)患者)。Pearson 系数显示两种方法之间的相关性为 0.793 (p < 0.001)。Hertel 测量的准确性与检查者的经验显著相关(< 5 年(组 1)、5-15 年(2)和> 25 年(3),p = 0.042,Kruskal-Wallis 分析;p = 0.086 组 1 与 2,p = 0.014 组 1 与 3,p = 0.688 组 2 与 3,Mann-Whitney-U 检验),反映在 Pearson 系数水平上(两种方法的相关性分别为 0.691 (组 1)、0.837 (2) 和 0.831 (3),p = 0.01)。总体而言,Hertel 突眼计与 CT 测量值相关性良好。亚组分析证实,经验丰富的检查者的 Hertel 测量质量更高。应改进对准确 Hertel 突眼计的教学。应实施使用标准化标准评估突眼的成像报告。