双钙钛矿型磁性 La2NiMnO6 纳米粒子在牛血清白蛋白吸附中的应用。

Department of Traditional Chinese Medicine of Nanfang Hospital, Southern Medical University, Guangzhou 510515, People's Republic of China.

Nanoscale Res Lett. 2013 May 2;8(1):207. doi: 10.1186/1556-276X-8-207.

Double-perovskite La2NiMnO6 (LNMO) nanoparticles were synthesized by co-precipitation process, and the adsorption of bovine serum albumin (BSA) protein on these nanoparticles was carried out. The powder samples were annealed at 750, 850, 950, and 1,050°C, respectively. X-ray diffraction (XRD) results reveal that there are double perovskites and exhibit mixed orientations, without any impurity phases. Transmission electron microscopy results as well as the XRD estimate results show that the crystalline size is about 34 to 40 nm. The adsorption of BSA on the magnetic nanoparticles was analyzed using a UV spectrophotometer at room temperature. The results show that the as-prepared LNMO nanoparticles display a good adsorbing ability for BSA, and the nanoparticle sintered at 850°C has the highest value of 219.6 mg/g, which is much higher than others.

采用共沉淀法合成了双钙钛矿 La2NiMnO6（LNMO）纳米粒子，并研究了牛血清白蛋白（BSA）在其表面的吸附。将所得粉末样品分别在 750、850、950 和 1050°C 下退火。X 射线衍射（XRD）结果表明，产物为具有混合取向的双钙钛矿，没有任何杂质相。透射电子显微镜（TEM）和 XRD 估算结果表明，晶体尺寸约为 34 到 40nm。在室温下使用紫外分光光度计分析了 BSA 在磁性纳米粒子上的吸附。结果表明，所制备的 LNMO 纳米粒子对 BSA 具有良好的吸附能力，在 850°C 下烧结的纳米粒子的吸附值最高，为 219.6mg/g，明显高于其他温度下的样品。