Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Hungária krt. 21, Budapest 1143, Hungary.
Vet Microbiol. 2013 Aug 30;165(3-4):190-9. doi: 10.1016/j.vetmic.2013.03.020. Epub 2013 Apr 4.
Group A rotavirus (RVA) infections cause severe economic losses in intensively reared livestock animals, particularly in herds of swine and cattle. RVA strains are antigenically heterogeneous, and are classified in multiple G and P types defined by the two outer capsid proteins, VP7 and VP4, respectively. This study summarizes published literature on the genetic and antigenic diversity of porcine and bovine RVA strains published over the last 3 decades. The single most prevalent genotype combination among porcine RVA strains was G5P[7], whereas the predominant genotype combination among bovine RVA strains was G6P[5], although spatiotemporal differences in RVA strain distribution were observed. These data provide important baseline data on epidemiologically important RVA strains in swine and cattle and may guide the development of more effective vaccines for veterinary use.
A 组轮状病毒（RVA）感染会给集约化饲养的牲畜造成严重的经济损失，特别是在猪和牛群中。RVA 株具有不同的抗原性，根据两个外壳蛋白 VP7 和 VP4 分别分为多个 G 和 P 型。本研究总结了过去 30 年来发表的关于猪和牛 RVA 株遗传和抗原多样性的文献。猪 RVA 株中最常见的基因型组合是 G5P[7]，而牛 RVA 株中主要的基因型组合是 G6P[5]，尽管在 RVA 株的分布上存在时空差异。这些数据为猪和牛中具有重要流行病学意义的 RVA 株提供了重要的基线数据，并可能为兽医用途的更有效疫苗的开发提供指导。
