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注意缺陷多动障碍增加了受伤的风险:一项基于人群的随访研究。

Attention-deficit/hyperactivity disorder increased the risk of injury: a population-based follow-up study.

机构信息

Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan.

出版信息

Acta Paediatr. 2013 Jun;102(6):640-3. doi: 10.1111/apa.12213.

Abstract

AIM

To explore the frequency and risk for injury among children with Attention-deficit/hyperactivity Disorder (ADHD) in Taiwan through a population-based study.

METHODS

A total of 3616 subjects aged between four and twelve years diagnosed with ADHD were selected along with a comparison cohort comprising 18 080 subjects. Each subject was individually traced for a three-year period from their index date to identify those subjects who subsequently received a diagnosis of injury. We used stratified Cox proportional hazards regressions to examine the three-year injury-free survival rates between the two cohorts.

RESULTS

Of the subjects, the incidence rate of injury during the three-year follow-up period was 7.97 (95% CI = 7.45-8.51) and 5.36 (95% CI = 5.17-5.56) for the study and comparison cohort, respectively. After adjusting for geographic region, the hazard ratio (HR) of injury for subjects with ADHD was 1.64 (95% CI = 1.50-1.79) that of comparison subjects. In addition, we found children with ADHD aged between four and 6 years to demonstrate a greater HR (1.98, 95% CI = 1.72-2.28) than those aged between seven and twelve (HR = 1.46, 95% CI = 1.31-1.63).

CONCLUSIONS

Children with ADHD appear to be at a higher risk for injury than children that are not diagnosed with ADHD.

摘要

目的

通过一项基于人群的研究,探讨台湾地区注意缺陷多动障碍(ADHD)儿童的受伤频率和受伤风险。

方法

共选取了 3616 名年龄在 4 至 12 岁之间被诊断为 ADHD 的儿童作为研究对象,并选取了 18080 名年龄匹配的对照儿童。从索引日期起对每位儿童进行为期 3 年的个体追踪,以确定随后被诊断为受伤的儿童。我们使用分层 Cox 比例风险回归来比较两组 3 年无损伤生存率。

结果

在 3 年的随访期间,研究队列和对照组的损伤发生率分别为 7.97(95%CI=7.45-8.51)和 5.36(95%CI=5.17-5.56)。调整地理区域后,ADHD 儿童的损伤风险比(HR)为 1.64(95%CI=1.50-1.79),高于对照儿童。此外,我们发现年龄在 4 至 6 岁之间的 ADHD 儿童的 HR 更高(1.98,95%CI=1.72-2.28),而 7 至 12 岁的儿童的 HR 较低(HR=1.46,95%CI=1.31-1.63)。

结论

与未被诊断为 ADHD 的儿童相比,ADHD 儿童似乎更易受伤。

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