Department of Computer Science, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada.
Bioinformatics. 2013 Jul 1;29(13):1693-5. doi: 10.1093/bioinformatics/btt265. Epub 2013 May 8.
While many experimentally characterized phosphorylation sites exist for certain organisms, such as human, rat and mouse, few sites are known for other organisms, hampering related research efforts. We have developed a software pipeline called DAPPLE that automates the process of using known phosphorylation sites from other organisms to identify putative sites in an organism of interest.
DAPPLE is available as a web server at http://saphire.usask.ca.
Supplementary data are available at Bioinformatics online.
尽管对于某些生物体(如人类、大鼠和小鼠)已经有许多经过实验验证的磷酸化位点,但对于其他生物体,已知的磷酸化位点却很少,这阻碍了相关的研究工作。我们开发了一个名为 DAPPLE 的软件流程,该流程可自动使用其他生物体中已知的磷酸化位点来识别感兴趣生物体中的潜在位点。
DAPPLE 可作为一个网络服务器在 http://saphire.usask.ca 使用。
补充数据可在《生物信息学》在线获得。