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生理浓度的葡萄糖会诱导膜泡分泌，并影响鼠疫耶尔森氏菌细胞表面的脂类和蛋白质组成。

Physiological levels of glucose induce membrane vesicle secretion and affect the lipid and protein composition of Yersinia pestis cell surfaces.

机构信息

School of Food Science, University of Idaho, Moscow, Idaho, USA.

出版信息

Appl Environ Microbiol. 2013 Jul;79(14):4509-14. doi: 10.1128/AEM.00675-13. Epub 2013 May 17.

DOI:10.1128/AEM.00675-13
PMID:23686263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3697494/
Abstract

Yersinia pestis grown with physiologic glucose increased cell autoaggregation and deposition of extracellular material, including membrane vesicles. Membranes were characterized, and glucose had significant effects on protein, lipid, and carbohydrate profiles. These effects were independent of temperature and the biofilm-related locus pgm and were not observed in Yersinia pseudotuberculosis.

摘要

鼠疫耶尔森菌在含有生理葡萄糖的条件下生长会增加细胞的自动聚集和细胞外物质的沉积，包括膜泡。对膜进行了特征分析，发现葡萄糖对蛋白质、脂质和碳水化合物图谱有显著影响。这些影响与温度和生物膜相关基因 pgm 无关，在假结核耶尔森菌中也没有观察到。

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Expert Rev Vaccines. 2012 Jun;11(6):659-61. doi: 10.1586/erv.12.34.
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