Institute for Environment and Development, Universiti Kebangsaan Malaysia, 43600, UKM, Bangi, Selangor D. E., Malaysia.
Asian Pac J Trop Med. 2013 Jun;6(6):462-6. doi: 10.1016/S1995-7645(13)60075-9.
To analyze trends of dengue incidences and deaths in Malaysia from 2000 to 2010 as well as the predominant dengue virus serotypes during the last decade.
We used the national data on annual reported cases, deaths, incidence rate, mortality rate, and case fatality rate of dengue fever (DF) and dengue hemorrhagic fever (DHF) as well as dengue virus serotypes prevalent in Malaysia during the last decade. Trend/ regression lines were fitted to investigate the trend of dengue incidences and deaths due to the disease for a 11-year period (2000-2010). For the distribution of national incidence rate, mortality rate, and case fatality rate of DF and DHF, descriptive statistics using mean and 95% confidence intervals (CI 39) for means, and range were applied.
The number of dengue cases and number of deaths have increased, on average, by 14% and 8% per year respectively. The average annual incidence rate of DF per 100 000 populations was higher as compared to that of DHF. Conversely, the yearly mean mortality rate of DHF per 100 000 populations was greater than that of DF. The simultaneous circulation of all four dengue serotypes has been found in Malaysia. But a particular dengue virus serotype predominates for at least two years before it becomes replaced by another serotype.
The dengue situation in Malaysia has worsened with an increasing number of reported cases and deaths during the last decade. The increasing trend of dengue highlights the need for a more systematic surveillance and reporting of the disease.
分析 2000 年至 2010 年马来西亚登革热发病率和死亡率的趋势，以及过去十年中主要的登革热病毒血清型。
我们使用了国家报告的年度病例、死亡人数、发病率、死亡率和病死率以及过去十年中马来西亚流行的登革热病毒血清型的数据。为了研究 11 年来登革热发病率和死亡率的趋势，我们拟合了趋势/回归线。对于全国登革热和登革出血热的发病率、死亡率和病死率的分布，应用了平均值和 95%置信区间（CI 39）的描述性统计，以及范围。
登革热病例和死亡人数平均每年分别增加 14%和 8%。每 10 万人中登革热的年平均发病率高于登革出血热。相反，每 10 万人中登革出血热的年平均死亡率大于登革热。马来西亚同时存在所有四种登革热血清型。但在被另一种血清型取代之前，一种特定的登革热病毒血清型至少会流行两年。
过去十年中，马来西亚的登革热情况恶化，报告的病例和死亡人数不断增加。登革热发病率的上升趋势表明需要更系统地监测和报告这种疾病。
