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一种光谱域光学相干断层扫描设备可在犬眼中提供可靠的角膜生物力学测量。

A spectral-domain optical coherence tomography device provides reliable corneal pachymetry measurements in canine eyes.

机构信息

Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA.

出版信息

Vet Rec. 2013 Jun 8;172(23):605. doi: 10.1136/vr.101530. Epub 2013 May 28.

Abstract

The objective of this study was to determine central corneal thickness (CCT) and the intra- and interuser reliability using a portable spectral-domain optical coherence tomography (SD-OCT) device in canine eyes. Twenty clinically normal dogs were examined. CCT measurements were obtained from both eyes of each animal three times by two operators in succession. The CCT was automatically calculated using the pachymetry software generated from eight radial scans, 6 mm in length. Mean canine CCT was 606.83±39.45 μm for all eyes examined. There was no significant difference in CCT based on the eye examined (OD vs OS), age or gender of the animal. There was no significant difference in CCT between replicates performed by the same operator; however, a small but significant difference was noted in CCT between operators. The mean difference in CCT between operators was 1.9 μm (P=0.03). The coefficient of variation for each user and between users was very low (range 0.64-1.7 per cent). The intraclass correlation coefficient comparing operators was 0.975. Based on these results, the SD-OCT device evaluated is capable of obtaining precise CCT measurements with excellent intra- and interoperator reliability in canine eyes.

摘要

本研究旨在使用便携式谱域光相干断层扫描(SD-OCT)设备测定犬眼的中央角膜厚度(CCT)和内-间用户可靠性。对 20 只临床正常犬进行了检查。由两名操作员连续三次对每只动物的双眼进行 CCT 测量。CCT 使用 8 条 6mm 长的径向扫描生成的测厚软件自动计算。所有检查眼的平均犬 CCT 为 606.83±39.45μm。CCT 与所检查的眼(OD 与 OS)、动物的年龄或性别无关,无显著差异。同一操作员进行的重复测量 CCT 无显著差异;然而,操作员之间的 CCT 有微小但显著的差异。操作员之间 CCT 的平均差异为 1.9μm(P=0.03)。每个用户和用户之间的变异系数非常低(范围为 0.64-1.7%)。操作员之间的组内相关系数为 0.975。基于这些结果,评估的 SD-OCT 设备能够在犬眼中获得精确的 CCT 测量,具有出色的内-间操作员可靠性。

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