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在疏油性 R(F)纸上快速制造压力驱动的开放式通道微流控器件。

Rapid fabrication of pressure-driven open-channel microfluidic devices in omniphobic R(F) paper.

机构信息

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.

出版信息

Lab Chip. 2013 Aug 7;13(15):2922-30. doi: 10.1039/c3lc50371b.

DOI:10.1039/c3lc50371b
PMID:23719764
Abstract

This paper describes the fabrication of pressure-driven, open-channel microfluidic systems with lateral dimensions of 45-300 microns carved in omniphobic paper using a craft-cutting tool. Vapor phase silanization with a fluorinated alkyltrichlorosilane renders paper omniphobic, but preserves its high gas permeability and mechanical properties. When sealed with tape, the carved channels form conduits capable of guiding liquid transport in the low-Reynolds number regime (i.e. laminar flow). These devices are compatible with complex fluids such as droplets of water in oil. The combination of omniphobic paper and a craft cutter enables the development of new types of valves and switches, such as "fold valves" and "porous switches," which provide new methods to control fluid flow.

摘要

本文描述了使用工艺切割工具在具有 45-300 微米横向尺寸的疏油纸上雕刻压力驱动的开放式微流控系统的方法。采用全氟烷基三氯硅烷的气相硅烷化处理使纸张具有疏油性,但保留了其高气透性和机械性能。用胶带密封后,雕刻的通道形成导管,能够在低雷诺数区域(即层流)引导液体输送。这些设备与复杂流体(如油包水液滴)兼容。疏油纸和工艺切割工具的结合使新型阀门和开关(如“折叠阀”和“多孔开关”)的开发成为可能,为控制流体流动提供了新的方法。

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