首次报道猪链球菌携带 cfr 多药耐药基因。
First report of the multiresistance gene cfr in Streptococcus suis.
机构信息
Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
出版信息
Antimicrob Agents Chemother. 2013 Aug;57(8):4061-3. doi: 10.1128/AAC.00713-13. Epub 2013 Jun 3.
Abstract
The multiresistance gene cfr was identified for the first time in streptococci, namely, in porcine Streptococcus suis isolate S10. The cfr gene was detected on the ~100-kb plasmid pStrcfr, where it was bracketed by two copies of the novel insertion sequence ISEnfa5, located in the same orientation. The detection of a cfr- and ISEnfa5-containing amplicon by inverse PCR suggests that ISEnfa5 may play a role in the dissemination of cfr.
摘要
cfr 耐药基因最初在链球菌中被发现，即在猪源链球菌 S10 分离株中。cfr 基因位于约 100kb 的质粒 pStrcfr 上，由两个新型插入序列 ISEnfa5 包围，方向相同。反向 PCR 检测到含有 cfr 和 ISEnfa5 的扩增子表明，ISEnfa5 可能在 cfr 的传播中起作用。
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