Ruiz Martínez M, Gil Extremera B, Maldonado Martín A, Cantero-Hinojosa J, Moreno-Abadía V
Centro Provincial de Drogodependencias (Provincial Center for Drug Addiction), Granada, España.
Klin Wochenschr. 1990 May 17;68(10):507-11. doi: 10.1007/BF01648242.
We studied trace elements (zinc, copper, magnesium, iron, and lithium) by atomic absorption spectrophotometry in the plasma and erythrocytes of 120 subjects: 20 healthy controls and 100 parenteral drug addicts (69 heroin and 31 heroin + other drugs). Plasma Zn and intraerythrocytic Zn and Fe were decreased, whereas plasma and intraerythrocytic Cu were significantly increased in the group of drug addicts with respect to the healthy controls. Moreover, a period of abstinence longer than 10 days was associated with lower plasma levels of Zn and Li in subjects who had taken drugs shortly before they were examined. The presence of serological markers against HBV and HIV did not seem to influence the behavior of the trace elements in blood.
我们采用原子吸收分光光度法对120名受试者的血浆和红细胞中的微量元素（锌、铜、镁、铁和锂）进行了研究，其中包括20名健康对照者和100名肠外药物成瘾者（69名海洛因成瘾者和31名海洛因加其他药物成瘾者）。与健康对照者相比，药物成瘾组的血浆锌、红细胞内锌和铁含量降低，而血浆和红细胞内铜含量显著升高。此外，在检查前不久服用过药物的受试者中，戒断期超过10天与血浆锌和锂水平较低有关。乙肝病毒和艾滋病毒血清学标志物的存在似乎不影响血液中微量元素的情况。
