Institute on Aging, University of Wisconsin-Madison, 1300 University Ave., 2245 MSC, Madison, WI 53706, USA.
Appetite. 2013 Oct;69:151-5. doi: 10.1016/j.appet.2013.05.020. Epub 2013 Jun 6.
The epidemic of obesity and its related chronic diseases has provoked interest in the predictors of eating behavior. Eating in response to stress has been extensively examined, but currently unclear is whether stress eating is associated with obesity and morbidity. We tested whether self-reported stress eating was associated with worse glucose metabolism among nondiabetic adults as well as with increased odds of prediabetes and diabetes. Further, we investigated whether these relationships were mediated by central fat distribution. Participants were 1138 adults (937 without diabetes) in the Midlife in the US study (MIDUS II). Glucose metabolism was characterized by fasting glucose, insulin, insulin resistance (HOMAIR), glycosylated hemoglobin (HbA1c), prediabetes, and diabetes status. Multivariate-adjusted analyses showed that stress eating was associated with significantly higher nondiabetic levels of glucose, insulin, insulin resistance, and HbA1c as well as higher odds of prediabetes or diabetes. Relationships between stress eating and all outcomes were no longer statistically significant once waist circumference was added to the models, suggesting that it mediates such relationships. Findings add to the growing literature on the relationships among psychosocial factors, obesity, and chronic disease by documenting associations between stress eating and objectively measured health outcomes in a national sample of adults. The findings have important implications for interventive targets related to obesity and chronic disease, namely, strategies to modify the tendency to use food as a coping response to stress.
肥胖及其相关慢性病的流行引起了人们对饮食行为预测因素的兴趣。人们广泛研究了应激时的进食行为,但目前尚不清楚应激性进食是否与肥胖和发病有关。我们检验了自我报告的应激性进食是否与非糖尿病成年人的葡萄糖代谢恶化有关,以及是否与糖尿病前期和糖尿病的发病风险增加有关。此外,我们还研究了这些关系是否通过中心性脂肪分布而产生影响。参与者为美国中年生活研究(MIDUS II)中的 1138 名成年人(937 名无糖尿病)。葡萄糖代谢通过空腹血糖、胰岛素、胰岛素抵抗(HOMAIR)、糖化血红蛋白(HbA1c)、糖尿病前期和糖尿病状态来进行特征描述。多变量调整分析表明,应激性进食与非糖尿病患者的葡萄糖、胰岛素、胰岛素抵抗和 HbA1c 水平显著升高以及糖尿病前期或糖尿病的发病风险增加有关。一旦将腰围纳入模型,应激性进食与所有结果之间的关系就不再具有统计学意义,这表明腰围在这些关系中起中介作用。这些发现通过记录应激性进食与成年人全国样本中客观测量的健康结果之间的关系,为心理社会因素、肥胖和慢性疾病之间的关系不断增加的文献增添了内容。这些发现对与肥胖和慢性疾病相关的干预目标具有重要意义,即改变以食物作为应激应对方式的倾向的策略。