School of Chemical Engineering, Oklahoma State University, Stillwater, Oklahoma, USA.
Int J Oral Maxillofac Implants. 2013 May-Jun;28(3):694-700. doi: 10.11607/jomi.2952.
The present study was conducted to determine whether biomechanical and histologic parameters would differ between implant surfaces blasted with bioactive ceramic resorbable media (biologic blasting) and blasted with alumina and acid-etched.
Fourteen beagle dogs were used. Eight animals received two implants of each surface per limb, and each limb provided samples that remained in vivo for 3 and 6 weeks. The other six animals received two implants of each surface in one limb, which remained in vivo for 1 week. After euthanization, half of the implants were subjected to torque-to-interface fracture; the other half of the implants were processed for nondecalcified histology to calculate bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO). Statistical analysis was performed with the Kruskal-Wallis test (95% level of significance).
While no significant differences were observed for BIC and BAFO between surfaces at all three times in vivo and for torque levels at 1 and 3 weeks, a significantly higher torque was observed for the biologic blasting group after 6 weeks in vivo. Bone morphology was similar between groups at all times.
A significant increase in early biomechanical fixation was observed for implants with the biologic blasting surface. However, no significant differences were observed for BIC and BAFO at any observation point.
本研究旨在确定使用生物活性陶瓷可吸收介质（生物喷砂）和氧化铝酸蚀处理喷砂的种植体表面的生物力学和组织学参数是否存在差异。
使用 14 只比格犬。8 只动物的每只肢体接受两种不同表面的植入物，每个肢体提供体内留存 3 周和 6 周的样本。其余 6 只动物的每条肢体接受两种不同表面的植入物，体内留存 1 周。安乐死后，一半的植入物进行界面扭矩断裂测试；另一半植入物进行非脱钙组织学处理，以计算骨-种植体接触（BIC）和骨面积占有率（BAFO）。采用 Kruskal-Wallis 检验（95%置信水平）进行统计分析。
在体内所有三个时间点以及 1 周和 3 周时，BIC 和 BAFO 以及扭矩水平在所有表面之间均无显著差异，但在体内 6 周时，生物喷砂组的扭矩明显更高。在所有时间点，两组的骨形态均相似。
生物喷砂表面的种植体在早期生物力学固定方面表现出显著增加。然而，在任何观察点都没有观察到 BIC 和 BAFO 的显著差异。
