University Department of Zoology, Ranchi University, Ranchi-834008, India.
Asian Pac J Trop Med. 2013 Jul;6(7):525-31. doi: 10.1016/S1995-7645(13)60090-5.
To study the potential ameliorating properties of cardamom Elettaria cardamomum (E. cardamomum) L. Maton against pan masala induced damage in lung of male Swiss mice.
The experimental animals were divided into 3 groups (control, pan masala treated group and pan masala with cardamom treated group) to evaluate pan masala toxicity. The observations were substantiated with profound changes in the lung tissue as revealed in the histologic and transmission electron microscopic examinations.
Lung of pan masala treated group showed adenocarcinoma, edema, and inflammation with increased activity of acid phosphatase, alkaline phosphatase, and lactate dehydrogenase. The deleterious effects were seen to be less in cardamom treated group and the enzymatic activity also decreased significantly (P<0.05) in the ameliorating group.
Thus, the present experiment exciting results are observed when cardamom is supplemented with pan masala, or when given alone.
研究小豆蔻 Elettaria cardamomum（E. cardamomum）L. Maton 对雄性瑞士小鼠潘那美拉诱导的肺部损伤的潜在改善特性。
将实验动物分为 3 组（对照组、潘那美拉处理组和潘那美拉加小豆蔻处理组），以评估潘那美拉的毒性。通过组织学和透射电子显微镜检查揭示的肺部组织的深刻变化来证实观察结果。
潘那美拉处理组的肺显示腺癌、水肿和炎症，酸性磷酸酶、碱性磷酸酶和乳酸脱氢酶活性增加。在小豆蔻处理组中观察到的有害影响较小，并且在改善组中酶活性也显著降低（P<0.05）。
因此，当小豆蔻与潘那美拉一起补充或单独给予时，观察到了令人兴奋的实验结果。
