Faculdade de Odontologia, Universidade Estadual Paulista (UNESP), Araçatuba, Brazil.
Caries Res. 2013;47(5):532-8. doi: 10.1159/000350229. Epub 2013 Jun 12.
The aim of this study was to investigate the effectiveness of sodium trimetaphosphate (TMP) addition to mouth rinses to inhibit enamel demineralization.
Bovine enamel blocks (n = 88) were selected by surface hardness and divided into eight treatment groups (n = 11 per group): placebo, 100 or 225 μg F/ml; the rinses with 100 μg F/ml had differing TMP concentrations (range 0-0.6%). The blocks were subjected to pH cycling for 5 days and treated twice a day with mouth rinses. After that, surface and cross-sectional hardness as well as fluoride in enamel were measured.
The groups containing both 100 μg F/ml and 0.4% TMP inhibited demineralization most effectively (p < 0.001). This formulation yielded lower values of lesion areas than the formulations containing 100 or 225 μg F/ml but no TMP. The addition of 0.4% TMP increased the fluoride in enamel.
It is possible to improve the effectiveness of a mouth rinse with 100 µg F/ml by addition of TMP, this being superior in inhibiting enamel demineralization compared with mouth rinses containing 225 µg F/ml.
本研究旨在探讨在漱口水中添加三聚磷酸钠（TMP）以抑制牙釉质脱矿的效果。
选择表面硬度一致的牛牙釉质块（n = 88），并将其分为 8 个治疗组（每组 n = 11）：安慰剂、100 或 225 μg F/ml；含 100 μg F/ml 的漱口水有不同浓度的 TMP（0-0.6%）。牙釉质块经 pH 循环 5 天，每天用漱口水处理两次。之后，测量表面和横截面硬度以及牙釉质中的氟含量。
同时含有 100 μg F/ml 和 0.4% TMP 的组对脱矿的抑制效果最有效（p < 0.001）。与含有 100 或 225 μg F/ml 但不含 TMP 的配方相比，该配方的病变面积值更低。添加 0.4% TMP 增加了牙釉质中的氟含量。
通过添加 TMP 可以提高含 100 μg F/ml 的漱口水的效果，其在抑制牙釉质脱矿方面优于含 225 μg F/ml 的漱口水。
