Fish and Fisheries Department, Faculty of Science, Shahrekord University, PO B 115, Shahrekord, Iran.
Ir Vet J. 2013 Jun 20;66(1):11. doi: 10.1186/2046-0481-66-11.
Cadmium (Cd), as one of heavy metals and an environmental stressor, may alter many physiological processes like growth and serum parameters in fish. The main objective of this study was to determine the effects of cadmium at sub-lethal concentrations (1 and 3 μg/l) on growth and serum biochemical parameters including enzymes, i.e. alkaline phosphatase (ALP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT), glucose, triglyceride, cholesterol and total protein in rainbow trout (Oncorhynchus mykiss). Trout were exposed to cadmium, and, at intervals of 1, 15, and 30 days, selected parameters were evaluated. Condition Factor (K), Specific Growth Rate (SGR) and Body Weight Gain (BWG) consistently decreased, while Food Conversion Ratio (FCR) increased at the end of experiment. Glucose was elevated in trout exposed to both Cd concentrations at day 15 and then returned to levels comparable to control fish. Triglyceride and cholesterol decreased transiently at day 15 and then increased at day 30. Total protein, AST, ALT and ALP increased linearly by time and Cd concentration. This investigation suggests that growth and serum biochemical parameters could be used as important and sensitive biomarkers in ecotoxicological studies concerning the effects of metal contamination and fish health.
镉 (Cd) 作为重金属和环境胁迫物之一，可能会改变鱼类的许多生理过程，如生长和血清参数。本研究的主要目的是确定亚致死浓度（1 和 3μg/l）的镉对虹鳟（Oncorhynchus mykiss）生长和血清生化参数的影响，包括酶，如碱性磷酸酶 (ALP)、天冬氨酸氨基转移酶 (AST) 和丙氨酸氨基转移酶 (ALT)、葡萄糖、甘油三酯、胆固醇和总蛋白。将鱼暴露于镉中，并在 1、15 和 30 天的间隔时间评估选定的参数。在实验结束时，条件因子 (K)、特定生长率 (SGR) 和体重增加 (BWG) 持续下降，而食物转化率 (FCR) 增加。在第 15 天，暴露于两种 Cd 浓度的鱼中的葡萄糖升高，然后恢复到与对照鱼相当的水平。甘油三酯和胆固醇在第 15 天短暂下降，然后在第 30 天增加。总蛋白、AST、ALT 和 ALP 随时间和 Cd 浓度呈线性增加。这项研究表明，生长和血清生化参数可以作为有关金属污染和鱼类健康影响的生态毒理学研究中的重要和敏感生物标志物。
