使用电子捕获气相色谱法和质量碎片谱法对水合氯醛作为三氯乙烯在人体中的瞬时代谢产物进行分离、表征和定量分析。
Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography.
作者信息
Cole W J, Mitchell R G, Salamonsen R F
出版信息
J Pharm Pharmacol. 1975 Mar;27(3):167-71. doi: 10.1111/j.2042-7158.1975.tb09431.x.
Abstract
A method for the quantitative determination of plasma concentrations of chloral hydrate by electron capture gas chromatography is described. Characterization by multiple ion monitoring confirms, for the first time, that chloral hydrate exists as a transient metabolite of trichloroethylene in man.
摘要
描述了一种通过电子捕获气相色谱法定量测定血浆中水合氯醛浓度的方法。通过多离子监测进行的表征首次证实，水合氯醛在人体内作为三氯乙烯的一种瞬时代谢产物存在。
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