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线粒体网络形态:构建一个综合的、几何的视角。

Mitochondrial network morphology: building an integrative, geometrical view.

机构信息

Department of Developmental and Cell Biology and Center for Complex Biological Systems, University of California, Irvine, CA 92697, USA.

出版信息

BMC Biol. 2013 Jun 24;11:71. doi: 10.1186/1741-7007-11-71.

Abstract

The morphology of mitochondrial networks is complex and highly varied, yet vital to cell function. The first step toward an integrative understanding of how mitochondrial morphology is generated and regulated is to define the interdependent geometrical features and their dynamics that together generate the morphology of a mitochondrial network within a cell. Distinct aspects of the size, shape, position, and dynamics of mitochondrial networks are described and examples of how these features depend on one another discussed.

摘要

线粒体网络的形态复杂多样,但对细胞功能至关重要。要综合理解线粒体形态的产生和调节机制,首先要确定共同生成细胞内线粒体网络形态的相互依存的几何特征及其动态。本文描述了线粒体网络大小、形状、位置和动态的不同方面,并讨论了这些特征之间的相互依赖关系的实例。

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