Colpo Elisângela, Vilanova Carlos Dalton de Avila, Brenner Reetz Luiz Gustavo, Medeiros Frescura Duarte Marta Maria, Farias Iria Luiza Gomes, Irineu Muller Edson, Muller Aline Lima Hermes, Moraes Flores Erico Marlon, Wagner Roger, da Rocha João Batista Teixeira
Department of Chemistry, Natural and Exact Sciences Centers, Federal University of Santa Maria (UFSM), 97105900 Santa Maria, RS, Brazil ; Department of Nutrition, Center Franciscan University (UNIFRA), Santa Maria, RS, Brazil.
J Nutr Metab. 2013;2013:653185. doi: 10.1155/2013/653185. Epub 2013 Jun 11.
Background. This study investigates the effects of Brazil nut ingestion on serum lipid profile in healthy volunteers. Methods. Ten healthy subjects were enrolled in the study. Each subject was tested 4 times in a randomized crossover in relation to the ingestion of different serving sizes of the Brazil nut: 0, 5, 20, or 50 g. At each treatment point, peripheral blood was drawn before and at 1, 3, 6, 9, 24, and 48 hours and 5 and 30 days. Blood samples were tested for total cholesterol, high- and low-density lipoprotein cholesterol (HDL-c and LDL-c, resp.), triglycerides, selenium, aspartate and alanine aminotransferases, albumin, total protein, alkaline phosphatase, gamma GT, urea, creatinine, and C-reactive protein. Results. A significant increase of the plasma selenium levels was observed at 6 hours within the groups receiving the nuts. Serum LDL-c was significantly lower, whereas HDL-c was significantly higher 9 hours after the ingestion of 20 or 50 g of nuts. The biochemical parameters of liver and kidney function were not modified by ingestion of nuts. Conclusions. This study shows that the ingestion of a single serving of Brazil nut can acutely improve the serum lipid profile of healthy volunteers.
背景。本研究调查了食用巴西坚果对健康志愿者血清脂质谱的影响。方法。10名健康受试者参与了本研究。每位受试者在随机交叉试验中接受了4次测试，分别涉及食用不同份量的巴西坚果：0、5、20或50克。在每个治疗点，于服用前以及服用后1、3、6、9、24和48小时以及5天和30天采集外周血。对血样进行总胆固醇、高密度和低密度脂蛋白胆固醇（分别为HDL-c和LDL-c）、甘油三酯、硒、天冬氨酸和丙氨酸转氨酶、白蛋白、总蛋白、碱性磷酸酶、γ-谷氨酰转移酶、尿素、肌酐和C反应蛋白检测。结果。在食用坚果的组中，6小时时血浆硒水平显著升高。食用20或50克坚果后9小时，血清LDL-c显著降低，而HDL-c显著升高。食用坚果未改变肝脏和肾脏功能的生化参数。结论。本研究表明，单次食用巴西坚果可急性改善健康志愿者的血清脂质谱。
