Olayinka Adeyeye Olufunke, Anthonia Ogbera, Yetunde Kuyinu
Department of Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
Indian J Endocrinol Metab. 2013 May;17(3):486-9. doi: 10.4103/2230-8210.111646.
In Nigeria, much has been reported on the unacceptably high disease burden of Tuberculosis (TB) and Diabetes Mellitus (DM) but not the possible co-existence of these diseases.
This study was conducted to document the co-existence of DM and TB in persons with established TB.
This was a cross-sectional study conducted at a Tertiary hospital's Directly Observed Therapy short course clinic in Lagos, South west, Nigeria.
Three hundred and fifty one consecutive patients with TB who consented to the study participated after a written consent. Ethical approval was given by the Ethics committee of the institution. Clinical examination for documentation of anthropometric indices and biochemical evaluation for blood glucose levels were carried out.
The prevalence of DM among the patients with TB was 5.7%. About half of the diabetics were diagnosed (2.8%) at the screening. The mean age of the participants was 34.9 ± 13.21 years; the mean duration of symptoms of TB was 9.65 ± 9.49 months. Weight (kg) loss was the most predominant symptom occurring in 94% of the patients. There was no significant difference in the sputum positivity and duration of cough among patients with TB-DM and those with TB alone.
Diabetes is an important co-morbid feature to be sought in patients with TB. This study re-echo the need to raise awareness on screening for DM in persons with TB.
在尼日利亚,关于结核病(TB)和糖尿病(DM)令人难以接受的高疾病负担已有很多报道,但尚未提及这两种疾病可能同时存在的情况。
本研究旨在记录确诊结核病患者中糖尿病和结核病同时存在的情况。
这是一项在尼日利亚西南部拉各斯一家三级医院的直接观察治疗短程诊所进行的横断面研究。
351名连续同意参与研究的结核病患者在签署书面同意书后参加了研究。该机构的伦理委员会给予了伦理批准。进行了人体测量指标记录的临床检查以及血糖水平的生化评估。
结核病患者中糖尿病的患病率为5.7%。约一半的糖尿病患者(2.8%)在筛查时被诊断出。参与者的平均年龄为34.9±13.21岁;结核病症状的平均持续时间为9.65±9.49个月。体重减轻是最主要的症状,94%的患者出现该症状。结核病合并糖尿病患者与单纯结核病患者在痰菌阳性率和咳嗽持续时间方面无显著差异。
糖尿病是结核病患者中需要关注的一个重要合并症特征。本研究再次强调了提高对结核病患者进行糖尿病筛查意识的必要性。