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Diabetes mellitus and HIV as co-morbidities in tuberculosis patients of rural south India.印度南部农村地区结核病合并糖尿病和 HIV 患者的情况。
J Infect Public Health. 2011 Aug;4(3):140-4. doi: 10.1016/j.jiph.2011.03.005. Epub 2011 Jun 14.
2
Tuberculosis and diabetes mellitus: convergence of two epidemics.结核病与糖尿病:两种流行病的交汇
Lancet Infect Dis. 2009 Dec;9(12):737-46. doi: 10.1016/S1473-3099(09)70282-8.
3
Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies.糖尿病会增加活动性肺结核的风险:对13项观察性研究的系统评价
PLoS Med. 2008 Jul 15;5(7):e152. doi: 10.1371/journal.pmed.0050152.
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Diabetes and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence.糖尿病与结核病:糖尿病流行对结核病发病率的影响。
BMC Public Health. 2007 Sep 6;7:234. doi: 10.1186/1471-2458-7-234.
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Type 2 diabetes and tuberculosis in a dynamic bi-national border population.动态双边边境人群中的2型糖尿病与结核病
Epidemiol Infect. 2007 Apr;135(3):483-91. doi: 10.1017/S0950268806006935. Epub 2006 Jul 25.
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Diabetes mellitus is strongly associated with tuberculosis in Indonesia.在印度尼西亚,糖尿病与结核病密切相关。
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Tuberculosis among diabetics: the Philadelphia survey.
Am Rev Tuberc. 1952 Jan;65(1:2):1-50.
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Pulmonary complications of diabetes mellitus. Pneumonia.糖尿病的肺部并发症。肺炎。
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尼日利亚拉各斯一家三级医疗中心结核病患者中糖尿病的患病率。

Prevalence of diabetes mellitus in persons with tuberculosis in a tertiary health centre in Lagos, Nigeria.

作者信息

Olayinka Adeyeye Olufunke, Anthonia Ogbera, Yetunde Kuyinu

机构信息

Department of Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.

出版信息

Indian J Endocrinol Metab. 2013 May;17(3):486-9. doi: 10.4103/2230-8210.111646.

DOI:10.4103/2230-8210.111646
PMID:23869307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3712381/
Abstract

CONTEXT

In Nigeria, much has been reported on the unacceptably high disease burden of Tuberculosis (TB) and Diabetes Mellitus (DM) but not the possible co-existence of these diseases.

AIM

This study was conducted to document the co-existence of DM and TB in persons with established TB.

SETTINGS AND DESIGN

This was a cross-sectional study conducted at a Tertiary hospital's Directly Observed Therapy short course clinic in Lagos, South west, Nigeria.

MATERIALS AND METHODS

Three hundred and fifty one consecutive patients with TB who consented to the study participated after a written consent. Ethical approval was given by the Ethics committee of the institution. Clinical examination for documentation of anthropometric indices and biochemical evaluation for blood glucose levels were carried out.

RESULTS

The prevalence of DM among the patients with TB was 5.7%. About half of the diabetics were diagnosed (2.8%) at the screening. The mean age of the participants was 34.9 ± 13.21 years; the mean duration of symptoms of TB was 9.65 ± 9.49 months. Weight (kg) loss was the most predominant symptom occurring in 94% of the patients. There was no significant difference in the sputum positivity and duration of cough among patients with TB-DM and those with TB alone.

CONCLUSION

Diabetes is an important co-morbid feature to be sought in patients with TB. This study re-echo the need to raise awareness on screening for DM in persons with TB.

摘要

背景

在尼日利亚,关于结核病(TB)和糖尿病(DM)令人难以接受的高疾病负担已有很多报道,但尚未提及这两种疾病可能同时存在的情况。

目的

本研究旨在记录确诊结核病患者中糖尿病和结核病同时存在的情况。

地点与设计

这是一项在尼日利亚西南部拉各斯一家三级医院的直接观察治疗短程诊所进行的横断面研究。

材料与方法

351名连续同意参与研究的结核病患者在签署书面同意书后参加了研究。该机构的伦理委员会给予了伦理批准。进行了人体测量指标记录的临床检查以及血糖水平的生化评估。

结果

结核病患者中糖尿病的患病率为5.7%。约一半的糖尿病患者(2.8%)在筛查时被诊断出。参与者的平均年龄为34.9±13.21岁;结核病症状的平均持续时间为9.65±9.49个月。体重减轻是最主要的症状,94%的患者出现该症状。结核病合并糖尿病患者与单纯结核病患者在痰菌阳性率和咳嗽持续时间方面无显著差异。

结论

糖尿病是结核病患者中需要关注的一个重要合并症特征。本研究再次强调了提高对结核病患者进行糖尿病筛查意识的必要性。