来自印度的两株人呼吸道合胞病毒A基因型毒株RSV-A/NIV1114046/11和RSV-A/NIV1114073/11的全基因组序列
Complete Genome Sequences of Two Human Respiratory Syncytial Virus Genotype A Strains from India, RSV-A/NIV1114046/11 and RSV-A/NIV1114073/11.
作者信息
Choudhary Manohar Lal, Wadhwa Bhumika S, Jadhav Santosh M, Chadha Mandeep S
机构信息
Human Influenza Department, National Institute of Virology, Pune, India.
出版信息
Genome Announc. 2013 Jul 25;1(4):e00165-13. doi: 10.1128/genomeA.00165-13.
Abstract
Two complete genomes of human respiratory syncytial virus subtype A (HRSV-A), with and without a 72-nucleotide duplication in the C-terminal glycoprotein G gene, were sequenced and analyzed. Characterization of these genomes will improve understanding of the diversity, emergence, virulence, pathogenicity, and transmissibility of a novel RSV-A genotype with a 72-nucleotide G gene duplication.
摘要
对两株人呼吸道合胞病毒A亚型（HRSV-A）的完整基因组进行了测序和分析，其中一株在C端糖蛋白G基因中存在72个核苷酸的重复，另一株不存在。对这些基因组的特征分析将有助于加深对具有72个核苷酸G基因重复的新型RSV-A基因型的多样性、出现、毒力、致病性和传播性的理解。
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