弗朗西斯菌的非典型脂多糖。
The atypical lipopolysaccharide of Francisella.
机构信息
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, United States.
出版信息
Carbohydr Res. 2013 Aug 30;378:79-83. doi: 10.1016/j.carres.2013.06.015. Epub 2013 Jul 2.
Abstract
Bacterial lipopolysaccharides (LPSs) are ubiquitous molecules that are prominent components of the outer membranes of most gram-negative bacteria. Genetic and structural characterizations of Francisella LPS have revealed substantial differences when compared to more commonly studied LPSs of the Enterobacteriaceae. This review discusses both the general characteristics and the unusual features of Francisella LPS.
摘要
细菌脂多糖（LPS）是普遍存在的分子，是大多数革兰氏阴性菌外膜的主要组成部分。与更常见的肠杆菌科 LPS 相比，弗朗西斯菌 LPS 的遗传和结构特征存在显著差异。本文讨论了弗朗西斯菌 LPS 的一般特征和独特特征。
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本文引用的文献
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Metabolic labeling to characterize the overall composition of Francisella lipid A and LPS grown in broth and in human phagocytes.代谢标记法分析在肉汤和人吞噬细胞中生长的弗朗西斯菌脂 A 和 LPS 的总体组成。
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Kdo hydrolase is required for Francisella tularensis virulence and evasion of TLR2-mediated innate immunity.Kdo 水解酶对于土拉弗朗西斯菌的毒力和逃避 TLR2 介导的固有免疫是必需的。
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