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Alcohol Alcohol. 2013 Nov-Dec;48(6):633-40. doi: 10.1093/alcalc/agt127. Epub 2013 Aug 7.
The aim of the study was to explore whether the concept of heavy substance use over time can be used as definition of substance use disorder.
Narrative review.
Heavy use over time clearly underlies the neurobiological changes associated with current thinking of substance use disorders. In addition, there is evidence that heavy use over time can explain the majority of social problems and of burden of disease (morbidity and mortality). A definition of substance use disorders via heavy use over time would avoid some of the problems of current conceptualizations, for instance the cultural specificity of concepts such as loss of control. Finally, stressing the continuum of use may avoid the high level of stigmatization currently associated with substance use disorders.
'Heavy substance use over time' seems to be a definition of substance use disorders in line with results of basic research and epidemiology. Additionally, it reduces stigmatization. This approach should thus be further explored.
本研究旨在探讨长期大量物质使用的概念是否可作为物质使用障碍的定义。
叙述性综述。
长期大量使用显然是与当前物质使用障碍相关的神经生物学变化的基础。此外,有证据表明,长期大量使用可以解释大多数社会问题和疾病负担(发病率和死亡率)。通过长期大量使用来定义物质使用障碍,可以避免当前概念化的一些问题,例如失去控制等概念的文化特异性。最后,强调使用的连续性可以避免目前与物质使用障碍相关的高度污名化。
“长期大量物质使用”似乎是符合基础研究和流行病学结果的物质使用障碍的定义。此外,它还减少了污名化。因此,这种方法应该进一步探讨。