Department of Infectious Diseases, Hospital Universitario de Bellvitge, Universidad de Barcelona, Barcelona, Spain.
J Infect. 2013 Dec;67(6):536-44. doi: 10.1016/j.jinf.2013.07.030. Epub 2013 Aug 7.
Infected hip hemiarthroplasties (HHA) are classically analyzed along with infected total hip arthroplasties (THA), but patients with either one or other device are different. We describe the clinical presentation, etiology and prognosis of infected HHA compared with infected THA.
Comparative study of patients with infected HHA and THA from a prospective database of prosthetic joint infection (PJI) cases in our hospital (2003-2011), focusing on patients managed with debridement, antibiotics and implant retention (DAIR).
210 episodes of hip-PJI (age 74 years, 63% women): 62 (39%) HHA and 148 (61%) THA. HHA-patients were older and had more comorbidities. Late-chronic and hematogenous infections were more frequent in THA. 123 (59%) patients were managed with DAIR: 72 THA and 51 HHA. Staphylococcus aureus was more frequent in THA (44% vs 26%, p = 0.032), while Gram-negative bacilli were more prevalent in HHA (73% vs 51%, p = 0.018), with a higher prevalence of fluoroquinolone-resistance in cemented-HHA. Overall failure was 37%, with no significant differences among groups. A higher mortality was observed in HHA cases (21% vs 4%, p = 0.005), particularly in cemented-HHA.
Infected THA and HHA have different characteristics, etiology and prognosis. Overall failure was similar, probably balanced by different predictors among groups, but mortality was higher among cemented-HHA.
感染性髋关节半髋关节置换术(HHA)与感染性全髋关节置换术(THA)一起进行经典分析,但使用这两种器械的患者有所不同。我们描述了与感染性 THA 相比,感染性 HHA 的临床表现、病因和预后。
对我院前瞻性假体关节感染(PJI)病例数据库中(2003-2011 年)感染性 HHA 和 THA 患者进行了比较研究,重点关注采用清创术、抗生素和保留植入物(DAIR)治疗的患者。
210 例髋关节 PJI(年龄 74 岁,63%为女性):62 例(39%)为 HHA,148 例(61%)为 THA。HHA 患者年龄较大,合并症较多。THA 中晚期慢性和血源性感染更为常见。123 例(59%)患者采用 DAIR 治疗:72 例 THA 和 51 例 HHA。THA 中金黄色葡萄球菌更为常见(44%比 26%,p=0.032),而 HHA 中革兰氏阴性杆菌更为常见(73%比 51%,p=0.018),水泥固定 HHA 中氟喹诺酮耐药率更高。总体失败率为 37%,各组间无显著差异。HHA 病例死亡率较高(21%比 4%,p=0.005),尤其是水泥固定 HHA。
感染性 THA 和 HHA 具有不同的特点、病因和预后。总体失败率相似,可能是由于各组之间的不同预测因素所平衡,但水泥固定 HHA 的死亡率较高。