Clinic for Clinical Neurophysiology, Universitätsmedizin, Georg-August-Universität Göttingen, Germany.
Front Hum Neurosci. 2013 Aug 5;7:435. doi: 10.3389/fnhum.2013.00435. eCollection 2013.
Transcranial electrical stimulation (tES) is a neuromodulatory method with promising potential for basic research and as a therapeutic tool. The most explored type of tES is transcranial direct current stimulation (tDCS), but also transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS) have been shown to affect cortical excitability, behavioral performance and brain activity. Although providing indirect measure of brain activity, functional magnetic resonance imaging (fMRI) can tell us more about the global effects of stimulation in the whole brain and what is more, on how it modulates functional interactions between brain regions, complementing what is known from electrophysiological methods such as measurement of motor evoked potentials. With this review, we aim to present the studies that have combined these techniques, the current approaches and discuss the results obtained so far.
经颅电刺激(tES)是一种具有很大发展潜力的神经调节方法,可用于基础研究和治疗工具。最受探索的 tES 类型是经颅直流电刺激(tDCS),但经颅交流电刺激(tACS)和经颅随机噪声刺激(tRNS)也已被证明可以影响皮质兴奋性、行为表现和大脑活动。尽管功能磁共振成像(fMRI)提供了大脑活动的间接测量,但它可以让我们更多地了解刺激对整个大脑的全局影响,更重要的是,它可以调节大脑区域之间的功能相互作用,补充了从电生理方法(如运动诱发电位测量)中已知的内容。通过这篇综述,我们旨在介绍结合这些技术的研究、当前的方法,并讨论迄今为止获得的结果。