Division of Nephrology, Seattle Children's Hospital, 4800 Sand Point Way NE, OC.9.820, Seattle, WA, 98105, USA,
Curr Hypertens Rep. 2013 Oct;15(5):417-25. doi: 10.1007/s11906-013-0382-z.
Elevation of blood pressure (BP) and the risk for progression to hypertension (HTN) is of increasing concern in children and adolescents. Indeed, it is increasingly recognized that target organ injury may begin with even low levels of BP elevation. Sodium intake has long been recognized as a modifiable risk factor for HTN. While it seems clear that sodium impacts BP in children, its effects may be enhanced by other factors including obesity and increasing age. Evidence from animal and human studies indicates that sodium may have adverse consequences on the cardiovascular system independent of HTN. Thus, moderation of sodium intake over a lifetime may reduce risk for cardiovascular morbidity in adulthood. An appetite for salt is acquired, and intake beyond our need is almost universal. Considering that eating habits in childhood have been shown to track into adulthood, modest sodium intake should be advocated as part of a healthy lifestyle.
血压升高(BP)和进展为高血压(HTN)的风险在儿童和青少年中越来越受到关注。事实上,人们越来越认识到,即使血压升高水平较低,靶器官损伤也可能开始。长期以来,人们一直认为钠的摄入量是高血压的一个可改变的危险因素。尽管似乎很清楚,钠会影响儿童的血压,但它的影响可能会因肥胖和年龄增长等其他因素而增强。动物和人类研究的证据表明,钠可能对心血管系统产生不良影响,而与高血压无关。因此,一生中适度摄入钠可能会降低成年后患心血管疾病的风险。对盐的偏好是后天获得的,摄入超过我们的需要几乎是普遍的。考虑到儿童时期的饮食习惯会一直延续到成年期,应该提倡适度摄入钠,作为健康生活方式的一部分。