Universidade Federal de Ciências da Saúde de Porto Alegre, Rua Sarmento Leite 245, Porto Alegre, RS, Brazil 90050-170.
Eur J Pediatr. 2013 Aug;172(8):1097-103. doi: 10.1007/s00431-013-2012-9. Epub 2013 May 1.
This study aimed to evaluate the effect of dietary sodium intake on blood pressure among low income children aged 3-4 years. Data were collected during a randomized trial conducted in São Leopoldo, Brazil, with 500 mother-child pairs recruited from the maternity ward of a local hospital. Breastfeeding data were obtained during the children's first year of life. At 3 to 4 years of age, children's anthropometric, dietary, and blood pressure assessments were obtained. Sodium intake was estimated from two multiple-pass 24-h dietary recalls. Systolic blood pressure > 90th percentile for age, sex, and height was classified as high systolic blood pressure, according to the population-based percentiles provided by the Task Force on Hypertension Control in Children and Adolescents. Blood pressure data were obtained from 331 children at 3 to 4 years. The mean value of systolic blood pressure was 91.31 mmHg (SD = 8.30 mmHg) and 5.2% (n = 17) presented high systolic blood pressure. The results of the multivariable analyses showed that children who consumed more than 1,200 mg of sodium/day and with waist-to-height ratio higher than 0.5 presented, respectively, 3.32 (95%CI 0.98-11.22) and 8.81 (95%CI 2.13-36.31) greater risk of having high systolic blood pressure. Exclusive breastfeeding, child overweight and change in body mass index z score during the first year of life were not associated with the outcome.
The results of this study suggest that at preschool age sodium intake and high waist-to-height ratio are risk factors for high systolic blood pressure.
本研究旨在评估低收入 3-4 岁儿童的钠摄入量对血压的影响。数据来自巴西圣莱奥波尔多进行的一项随机试验,该试验从当地医院的产科病房招募了 500 对母婴。在儿童生命的第一年获得母乳喂养数据。在 3 至 4 岁时,评估儿童的人体测量,饮食和血压。通过两次多次 24 小时饮食回忆来估算钠摄入量。根据儿童和青少年高血压控制工作组提供的基于人群的百分位数,将收缩压>年龄,性别和身高的第 90 百分位数定义为收缩压高。在 3 至 4 岁时从 331 名儿童中获得血压数据。收缩压的平均值为 91.31mmHg(SD=8.30mmHg),5.2%(n=17)表现为收缩压高。多变量分析的结果表明,每天摄入超过 1200mg 钠和腰高比高于 0.5 的儿童,分别有 3.32(95%CI 0.98-11.22)和 8.81(95%CI 2.13-36.31)更高的发生收缩压高的风险。纯母乳喂养,儿童超重和生命第一年体重指数 z 分数的变化与结果无关。
这项研究的结果表明,在学龄前,钠摄入量和高腰高比是收缩压高的危险因素。