Hematology-Oncology Division, Department of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.
Saudi Pharm J. 2013 Apr;21(2):165-8. doi: 10.1016/j.jsps.2012.05.008. Epub 2012 May 26.
AIM/BACKGROUND: Treatment of DVT with LMWHs has been shown recently to be as effective as UFH with suggested lower costs. This study was conducted to determine and compare the cost of in-patient hospital treatment versus outpatient hospital treatment of patients with DVT.
All adult patients with acute proximal DVT referred to the Emergency Department of King Khalid University Hospital, Riyadh, Saudi Arabia between August 2009 and August 2010 were invited to the study. An economic analysis was performed to compare the cost impact of outpatients versus hospital treatment.
Sixty-one patients were included in the study, 31 were followed in the outpatient setting and 30 as the control group (inpatients). There were no significant differences in the outcome between the outpatient and inpatient group; three patients (9.7%) in the outpatient group and four patients (13.3%) in the inpatient group had recurrent DVT. Mean nursing cost was $55 for the outpatient group and $215 for the inpatient group, mean laboratory monitoring cost was $638 for outpatient group and $1511 for the inpatient group. Hospital stay and doctor's fees amounted to a mean of $1000 for outpatient treatment and $2387 for inpatient treatment, p < 0.0001. The mean outpatient cost was significantly lower than the inpatient cost ($1750 vs. $4338, p < 0.0001).
Outpatient treatment of patients with DVT using LMWHs is cost-effective with no significant differences in the outcome of patients. OPD treatment of DVT is feasible in Saudi Arabia provided there is enough logistic support from thrombosis clinics and those involved in DVT care.
目的/背景:最近的研究表明,低分子肝素(LMWHs)治疗 DVT 的效果与普通肝素(UFH)相当,且成本更低。本研究旨在确定和比较 DVT 患者住院治疗与门诊治疗的成本。
本研究邀请了 2009 年 8 月至 2010 年 8 月间在沙特阿拉伯利雅得 King Khalid 大学医院急诊科就诊的所有急性近端 DVT 成年患者参与。进行了一项经济分析,以比较门诊治疗和住院治疗的成本影响。
本研究共纳入 61 例患者,其中 31 例在门诊接受治疗,30 例作为对照组(住院患者)。门诊组和住院组的结果无显著差异;门诊组有 3 例(9.7%)患者和住院组有 4 例(13.3%)患者出现复发性 DVT。门诊组的护理费用平均为 55 美元,住院组为 215 美元;门诊组的实验室监测费用平均为 638 美元,住院组为 1511 美元。门诊治疗的住院和医生费用平均为 1000 美元,住院治疗为 2387 美元,p<0.0001。门诊治疗的平均费用明显低于住院治疗(1750 美元 vs. 4338 美元,p<0.0001)。
使用 LMWHs 对 DVT 患者进行门诊治疗是具有成本效益的,且患者的治疗结果无显著差异。在沙特阿拉伯,只要血栓门诊和参与 DVT 治疗的人员提供足够的后勤支持,门诊治疗 DVT 是可行的。