库拉索芦荟高分子量部分对 2 型糖尿病患者可能的降血糖作用。
Possible hypoglycemic effect of Aloe vera L. high molecular weight fractions on type 2 diabetic patients.
机构信息
Placenta/Aloe Research Institute, Japan Bio Products Co. Ltd., 1-1Hyakunen-koen, Kurume-shi, Fukuoka 839-0864, Japan.
出版信息
Saudi Pharm J. 2009 Jul;17(3):209-15. doi: 10.1016/j.jsps.2009.08.007. Epub 2009 Aug 7.
Abstract
Aloe vera L. high molecular weight fractions (AHM) containing less than 10 ppm of barbaloin and polysaccharide (MW: 1000 kDa) with glycoprotein, verectin (MW: 29 kDa), were prepared by patented hyper-dry system in combination of freeze-dry technique with microwave and far infrared radiation. AHM produced significant decrease in blood glucose level sustained for 6 weeks of the start of the study. Significant decrease in triglycerides was only observed 4 weeks after treatment and continued thereafter. No deterious effects on kidney and liver functions were apparent. Treatment of diabetic patients with AHM may relief vascular complications probably via activation of immunosystem.
摘要
库拉索芦荟高分子量部分（AHM）中巴拉巴灵含量低于 10ppm，多糖（MW：1000kDa）与糖蛋白、韦拉特辛（MW：29kDa）一起，采用专利超干系统结合冷冻干燥技术与微波和远红外线辐射制备而成。AHM 可显著降低血糖水平，在研究开始后的 6 周内持续下降。仅在治疗 4 周后观察到甘油三酯显著下降，此后持续下降。对肾功能和肝功能无明显损害作用。AHM 治疗糖尿病患者可能通过激活免疫系统缓解血管并发症。
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