Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, Fukuoka, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Oct;116(4):433-9. doi: 10.1016/j.oooo.2013.05.021. Epub 2013 Aug 19.
The aim of the study was to evaluate the effect of mouth cleaning with hinokitiol-containing gel on oral malodor.
An open-label, randomized, controlled trial was conducted to assess oral malodor and clinical parameters related to oral malodor before and after mouth cleaning with hinokitiol-containing gel (n = 9) or with gel not including hinokitiol (n = 9). Mouth cleaning included the teeth, gingiva, and tongue and was carried out 3 times per day for 4 weeks.
Organoleptic test (OLT) scores (P = .021), levels of hydrogen sulfide (P = .008) and methyl mercaptan (P = .020), frequency of bleeding on probing, average probing pocket depth, and plaque index significantly improved in the group using hinokitiol. In contrast, only the OLT score (P = .031) significantly improved in the control group after the treatment regimen.
Mouth cleaning with hinokitiol-containing gel may be effective for reduction of oral malodor.
本研究旨在评估含桧木醇凝胶进行口腔清洁对口腔异味的影响。
采用开放性、随机、对照试验，评估使用含桧木醇凝胶（n=9）或不含桧木醇凝胶（n=9）进行口腔清洁前后的口腔异味和与口腔异味相关的临床参数。口腔清洁包括牙齿、牙龈和舌头，每天进行 3 次，持续 4 周。
感觉测试（OLT）评分（P=.021）、硫化氢水平（P=.008）、甲硫醇水平（P=.020）、探诊出血频率、平均探诊袋深度和菌斑指数在使用桧木醇的组中显著改善。相比之下，在治疗后，对照组仅 OLT 评分（P=.031）显著改善。
含桧木醇凝胶进行口腔清洁可能对减少口腔异味有效。
